The primary diagnostic endoscopic methods for connective tissue diseases verification in patients with respiratory manifestations
Journal Title: Хірургія України - Year 2019, Vol 0, Issue 2
Abstract
The aim — to conduct a retrospective analysis of the connective tissue diseases diagnosis in 47 patients of different ages with respiratory manifestations. Materials and methods. A clinical analysis of the first diagnosed cases of connective tissue diseases in 47 patients treated on the basis of the department of thoracic surgery and invasive diagnostic methods, from 2010 to 2018 was done. Among patients, women predominated — 33 (70.2 %), men — 14 (29.8 %). Among them, at the age of 20 — 29 years old, there were 8 (16.8 %) patients; 30 — 39 years — 14 (29.8 %) patients; 40 — 49 years old — 12 (25.5 %); 50 — 59 years old — 9 (19.5 %); over the age of 60 years‑ 4 (8.4 %). The patients were hospitalized with the following diagnoses: disseminated pulmonary disease — 10 (21.3 %), disseminated pulmonary disease complicated by unilateral pleurisy — 12 (25.5 %) patients; disseminated pulmonary disease complicated by bilateral pleurisy — 1 (2.1 %) case; disseminated pulmonary disease complicated by unilateral pleurisy and intrathoracic lymphadenopathy — 2 (4.3 %) observations; rounded lung lesion — 1 (2.1 %) case; unilateral pleurisy— 4 (8.4 %); bilateral pleurisy — 6 (12.9 %); pleurisy with pericarditis — 11 (23.4 %) cases. Results and discussion. In all cases, the specificity of the autoimmune lesion was identified. The attention is paid to the need for early diagnosis of this pathology and the adequate pathogenic treatment appointment by profile specialists. Conclusions. Of newly diagnosed patients with total respiratory, cardiovascular and renal impairment without any history of chronic disease should be considered as a risk group for further diagnosis of connective tissue diseases. The use of video‑assisted thoracoscopic surgery diagnostic methods with biopsy of affected tissues should be the standard of study along with immunological confirmation when establishing the type of connective tissue diseases. The connective tissue diseases type identification should be done considering the clinical manifestations, based on the pathomorphological study results and the serological verification by specialists, since the nosology type establishment timely contributes to the immunopathological syndromes detection and allows the immune‑dependent complications prevention by adequately prescribed pathogenically valid treatment.
Authors and Affiliations
M. S. Opanasenko, L. I. Levadna, O. V. Tereshkovych, B. M. Konik, V. B. Bychkovskyi, I. V. Liskina, L. M. Zagaba, M. I. Kalenychenko, S. M. Shalagai, M. Yu. Shamrai, V. I. Lysenko, O. K. Obremska
Keywords
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- EP ID EP609794
- DOI 10.30978/SU2019-2-61
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