The qualitative composition and quantitative content of flavonoids in the aerial part of the speciesbelonging to subfamily Nepetoideae family Lamiaceae
Journal Title: Фармацевтичний журнал - Year 2015, Vol 4, Issue 4
Abstract
Eessential oil herbs have long been used in medicine as anti-inflammatory, antispasmodic, antibacterial, expectorant and sedative drugs. At present phenolic compounds including flavonoids, play an important role in the total biological activity of essential oilplants. The aim of this research – the identification and analysis of flavonoids in the aerial parts of three species belonging to the subfamily Nepetoideae family Lamiaceae: Ocimum americanum, Lophanthus anisatus and Satureja hortensis. It was identified the flavonoids by used qualitative reactions and chromatographic methods: paper, thin-layer and high performance liquid chromatography. It was detected the presence of a number of aglycone and glycoside flavonoids. It was found the flavonol (rutin, isoquercitrin and hyperoside) and flavone (apigenin, luteolin and their derivatives) compounds. Lophanthus anisatus is characterized the highest diversity of flavonoids. Ir was revealed the presence of isoquercitrinand luteolin derivatives in all investigated plants; other compounds was detected selectively. Lophanthus anisatus herb set the maximum content of apigenin and its derivatives ((30,71·10-2% и 26,79·10-2%, respectively); the highest content of rutin was found in the grass Ocimum americanum (62,06·10 2%) and Satureja hortensis (28,56·10-2%). The results of investigations can be used in chemotaxonomy of the subfamily Nepetoideae and further planning of pharmacological studies.
Authors and Affiliations
M. I. Shanayda
Keywords
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