The Relationship between Androgenic Alopecia and Prostate Cancer
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2016, Vol 5, Issue 7
Abstract
Prostate cancer (PC) and Androgenic Alopecia (AGA) i are both common diseases in elder men. It seems that androgen plays a crucial role in the growth and development of prostate cancer. Therefore, the current study intended to investigate the relationship between androgenic alopecia and prostate cancer. The present study is a case-control study conducted on 75 patients with prostate cancer (case group) referring to Imam Khomeini Hospital in Sari, Iran. The case group was compared with the control group (75 healthy individuals). The intended questionnaire of the study included information such as the age, sex, duration of disease, stage of disease, level of PSA, time diagnosis and time of interview for all the participants. The results of interview and clinical examination along with the patient’s information all were filled in the questionnaire and were statistically analyzed by SPSS after data collection. The mean age of PC group and healthy group was respectively 69.08 ± 8.97 and 68 .45 ± 10.16 years. The average level of PSA was 10.86 ± 11.7 and 2.66 ± 2.7 ng/ml in PC and healthy group in turn. The average duration of cancer was 12.63 ± 9.19 months in PC group. Furthermore, about 6.7% of cancer patients were in stage I, 48% were stage II, 29.3% were in stage III and 16% were in stage IV of prostate cancer. Besides, the number of cancer patients who had both frontal and vertex alopecia (baldness) altogether exceeded healthy individuals (P=0.002). According to the results of the present study, there was a significant relationship between prostate cancer and androgenic alopecia which might have been caused by the effect of androgens on both diseases. Consequently, androgenic alopecia can be considered as one of the risk factors associated with prostate cancer.
Authors and Affiliations
Ghasem Rahmatpour Rokni| Assistant Professor of dermatology Bo Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran, Ali Morad Heidari Gorji| Assistant Professor (EDC), Mazandaran University of Medical Sciences, Sari, Iran, Mahnaz Sharifian| Patologist Bo Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran, Amir Hossein Rezaei Talarposhti| General medicine Bo Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran, Ayub Barzgarnejad| Assistant Professor of urology Emam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran Corresponding Email: ayubbarzarnejad@gmail.com
Keywords
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