The Relationship between SYNTAX Score and Resting/Post-exercise Ankle-Brachial index in Patients with Acute Coronary Syndrome
Journal Title: International Journal of Current Medical and Biological Sciences - Year 2022, Vol 2, Issue 2
Abstract
Background: The aim of this study is to determine the relationship between the complexity of coronary artery disease (CAD), determined by the SYNTAX score, and the resting and post-exercise Ankle-Brachial Index (ABI). Materials and Methods: Patients who were treated for Acute Coronary Syndrome (ACS) were evaluated in our study. The patients were divided into two groups according to their SYNTAX Score ≤22 or >22. In addition, patients were evaluated in two groups as <30 and ≥30 in the SYNTAX II (PCI) scoring. The measurements of the resting ABI and the post-exercise ABI were done in these patients.Results: The mean age of 118 patients was 57.50±11.19 years and 26 (22%) patients were female. In the group with SYNTAX Score>22, lower resting ABI (p <0.001) and post-exercise ABI (p <0.001) were observed, whereas the higher SYNTAX II PCI (p= 0.005) score was found. While lower resting ABI (p<0.001) and post-exercise ABI (p<0.001) were observed in the group with SYNTAX II PCI Score ≥30, TIMI (0.015), GRACE score (0.004) and SYNTAX score (p= 0.001) were higher. As a result of the ROC analysis: resting ABI cut-off value was detected as 0.935 with a sensitivity of 75% and a specificity of 75% [p<0.001; AUC(95% CI)= 0.786 (0.697-0.875)] and post-exercise ABI cut-off value was detected as 0.945 with a sensitivity of 80% and a specificity of 81% to predict SYNTAX score >22 [p <0.001; AUC (95% CI)= 0.836 (0.761-0.912)]. Diabetes mellitus, history of CAD, resting and post-exercise ABI variables were found to be independent predictors of the extent of CAD, expressed as SYNTAX score >22 and SYNTAX II PCI score ≥30.Conclusion: In ACS patients, post-exercise ABI measurements have a stronger diagnostic power than resting ABI measurements in predicting CAD complexity. ABI measures at resting and post-exercise are independent predictors of CAD complexity in ACS patients.
Authors and Affiliations
Emre Yılmaz, Ayşenur Güllü, Muammer Karakayalı, Ali Rıza Demir, Ertan Aydın, Mehmet Ertürk
Keywords
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