The Relationship Between the Leptin and Vitamin D Levels in Postmenapausal Women
Journal Title: HASEKİ TIP BÜLTENİ - Year 2018, Vol 56, Issue 3
Abstract
Aim: To determine the relationship of leptin with vitamin D and parathormone (PTH) levels in postmenopausal women who have no osteoporosis and to evaluate the effect of these three parameters on bone mineral dansity and bone homeostasis. Methods: Sixty-eight postmenopausal patients with no osteoporosis, who attended the general internal medicine, geriatric and endocrinology outpatient clinics between November 2013 and June 2014, were included in the study. The patients were divided into two groups according to vitamin D levels. Results: Group 1 consisted of 27 patients with low vitamin D levels and group 2 consisted of 41 patients with normal vitamin D levels. Two groups were similar in terms of age, age of menopause and body mass index (BMI). The mean PTH level and the mean leptin level in group 1 were statistically significantly higher than in group 2 (p= 0.01; p=0.01, respectively). There was no significant correlation between leptin and PTH in group 1 (r=0.16, p=0.4), however, a positive correlation was observed in group 2 (r=0.46, p=0.002). We found a significant positive correlation between leptin and BMI in both groups (r=0.40, p< 0.01). No significant correlation was found between leptin and vitamin D in both groups. Conclusion: In our study, the high leptin levels in postmenapasaul women having low vitamin D levels without osteoporosis or obesity may suggest the role of leptin in the prevention of osteoporosis.
Authors and Affiliations
Hakan Yavuzer, Afrodita Zeynep Taşkın, Filiz Demirdağ, İbrahim Murat Bolayırlı, Alper Döventaş, Deniz Suna Erdinçler
Keywords
Related Articles
- EP ID EP392683
- DOI 10.4274/haseki.3831
- Views 78
- Downloads 0
Quantitative Analysis of Osteoporotic Vertebral Fracture Risk on Pre-Existing CT
Aim: Recent research has shown that the measurement of vertebrae bone density on computed tomography for diagnosis of osteoporosis is associated with dual energy X-ray absorptiometry. Our aim was to compare vertebra bone...
Evaluation of Patients Diagnosed with Incidental Gallbladder Cancers After Cholecystectomy
Aim: In this study, we evaluated the incidence of incidentel gallbladder cancer patients etiologic factors who underwent cholecystectomy in our clinic. Methods: Between January 2010 and December 2017, 3691 patients who u...
Assesment of the Approach to the Painless Delivery: A Survey Study
Aim: Being able to relieve pain that occurs during delivery provides physical and emotional involvement of the mother in the birth and could reduce maternal and fetal undesirable effects. We planned this questionnaire st...
Synchronous Bilateral Male Breast Cancer: A Rare Case Report
Male breast cancer accounts for less than 1% of all breast carcinomas and 0.17 to -1.5% of all cancers seen in men. The incidence of synchronous bilateral male breast cancer has been reported to be 1.5%-2% of all male br...
Congenital Transmesenteric Hernia Without Bowel Strangulation in a Young Adult
Congenital internal hernia is a rare cause of bowel obstruction in adults and often presents with complications. A high index of suspicion, occasionally aided by appropriate radiological imaging, should lead to early sur...