The role of adenosine A2A receptors in antidepressant activity in experimental animal model of depression
Journal Title: Medicina Internacia Revuo - Year 2017, Vol 27, Issue 109
Abstract
Intensive studies on the role of adenosine A2A receptors in Parkinson's disease have been carried out for many years,. These studies have indicated that the antagonists of these receptors not only alleviate motor deficits but also exhibit neuroprotective effects in various animal models. Little is known about the role of these receptors in ailments accompanying Parkinson's disease, such as depression and anxiety. This paper provides a summary of existing research on the role of A2A receptors in comorbid depression in Parkinson's disease.
Authors and Affiliations
Anna Dziubina, Małgorzata Zygmunt, Barbara Filipek, Kinga Sałat, Adrian Bryła, Tadeusz Librowski, Joanna Gdula-Argasińska
Keywords
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