The Role of Microbiota in Manifestation of Extrusion Food Products’ Side Effects
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2018, Vol 7, Issue 3
Abstract
Significance of various types of diets for the organism in health and disease is well known. For example, Mediterranean diet is usually associated with longevity of Mediterranean region inhabitants. On the other hand, intake of poor-quality food products is accompanied with development of acute and chronic diseases of gastrointestinal tract. Therefore, it is understandable why ancient doctors used to place emphasis on diets. Nowadays these beliefs evolved into scientific fields substantiating importance of diets’ heat value, optimal content of proteins, fats, carbohydrates, vitamins, minerals, etc. Unfortunately, the increase of knowledge in this scientific area is accompanied with the growth of morbidity, which is directly or indirectly connected with intake of food products; also medical expenses on treatment of these patients grow [1,2]. The search for “morbidity quality food intake” revealed 2460 articles in PubMed on July 21, 2018. The authors have chosen contentious topic among the range of problems in this field: the functional significance of extrusion food products in the scope of increasing consumer interest, especially in children and teens. Extrusion Food Products Scientific articles adduce both pros [3] and cons [4] of extrusion food products intake. For example, there are evidences that experimental rats died in two weeks after consumption of food based on extrusion products. The assumption about toxic products in food [4] seems impossible. Strange, but that social problem generates mild interest. The search for “extrusion food prospects” revealed one article in PubMed on July 21, 2018 [3], but “extrusion food side effects” 62 articles. The articles about side effects describe lowering of free lysine in extruded samples [5], change of their physical and chemical properties [6], ochratoxin A transformation [7] and structural changes in mycotoxins [8]. Therefore, the facts speak for presence of side effects after intake of existent extrusion food products. Consequences of Extrusion Food Consuming: Experimental Analysis Above mentioned became stimulus to verify hypothesis on the mechanisms of negative effects development up to lethal outcomes [4] during regular intake of extrusion food products. Male Wistar rats (n=15) weighing 173.6±11.7 g were divided into three equal groups in pilot project. Animals from the first group received standard food ration, the ones from the second group – the same amount of ration consisting of extrusion products (dry cereal breakfast, confectionary “Matyash”, Tula, Russian Federation). The animals from the third group received the 1:1 mixture of two above mentioned rations. All the animals were kept in equal standard vivarium conditions. Mann-Whitney test revealed statistically significant (p≤0.01) decrease in body mass of rats receiving extrusion food products only in one and two weeks after beginning of the experiment compared to other groups. In fact, the mass of animals in the second group did not differ from the baseline. The experiment with different types of rations was finished at this stage and all the animals began receiving standard food ration. Body mass of all the rats did not differ statistically in two weeks after transfer to standard food ration.
Authors and Affiliations
Rubakhova Valentina, Zamaro Alexandra, Grinchik Nikolay, Larchenko Maria, Koulchitsky Stanislav, Loiko Diana, Derevyanko Irina, Sushko Timur, Chuprina Alesya, Kuznetsova Tatiana, Stukach-Takalchyk Yuliya, Kulchitsky Vladimir
Keywords
Related Articles
- EP ID EP592766
- DOI 10.26717/BJSTR.2018.07.001503
- Views 154
- Downloads 0
Nucleotide Variations in microRNA-Binding Sites: The Need of Novel Tools for the Nucleic Acid Alignment
It has been proposed that naturally-occurring variations in microRNAs and their target sites on messenger RNAs may be linked with various human pathologies, including cancer. The growing number of reports clearly indicat...
Screening of Oropharyngeal Dysphagia in Patients with Diabetes Mellitus
Background: Diabetes mellitus is a systemic endocrinal disease that results either from deficiency of insulin hormone (type 1) or from insulin resistance or both (type 2). Literature is scarce related to dysphagia with d...
Rosmarinus Officinalis (Rosemary): A Novel Therapeutic Agent for Antioxidant, Antimicrobial, Anticancer,Antidiabetic, Antidepressant, Neuroprotective, Anti-Inflammatory, and Anti-Obesity Treatment
Objective: Collect published research articles on the desired topic and summarizes their findings in an evaluation of the preservative and therapeutic potential of Rosmarinus officinalis. Design: The research articles us...
Acute Sensory Neuropathy and Progressive Dysphagia with Anti-GQ1b Antibody Positive: A Case Report
Anti-GQ1b ganglioside antibody is associated with ophthalmoplegia, ataxia, and areflexia, resulting in the development of Miller Fisher Syndrome (MFS), Guillain-Barré Syndrome (GBS) with ophthalmoplegia and Bickerstaff b...
The Anterolateral Thigh Flap: Clinical Applications and Review of the Literature
The anterolateral thigh (ALT) flap has gained popularity in reconstructive surgery in recent years as its advantages have come to be widely recognized. We report the senior author’s experience over a five-year period wit...