The role of miRNAs in autoimmune inflammatory diseases

Journal Title: International Journal of Clinical Rheumatology - Year 2018, Vol 13, Issue 6

Abstract

MicroRNAs (miRNAs) are abundant short 21- 23 nucleotides-long non-coding RNAs that modulate virtually all eukaryotic gene expression processes during development and are crucial for sustaining optimal cell functions and tissue homeostasis. The potential of miRNAs as biomarkers and/or therapeutic targets in rheumatic diseases is a new area of research for which currently available data are promising and expanding but still limited.

Authors and Affiliations

Federica Canzano, Alessia Paganelli, Paola Volpe, Roberto Paganelli

Keywords

Related Articles

Synovial fluid level of vascular endothelial growth factor (VEGF) can predict functional status and radiological severity in patients with knee osteoarthritis (OA)

Aim of the work: Detection of serum and synovial fluid level of Vascular Endothelial Growth Factor (VEGF) in patients with knee osteoarthritis (OA) and to determine its relation to radiological severity and function stat...

HLA class I and II alleles may influence susceptibility to adult dermatomyositis in a Mexican mestizo population

Objective: To investigate the possible association between HLA and Dermatomyositis (DM) in the Mexican mestizo population. Methods: HLA class I (A and B) and class II (DRB1* and DQB1*) were determined in 36 Mexican mest...

Rheumatology to hepatology cross talk: An evidence based update on the treat to target strategy in hepatitis-C related extrahepatic autoimmune syndromes

Hepatitis C virus (HCV) is a universally identified major epidemiological health problem with an estimated reservoir of almost 200 million or 3% of the global population. In the year 2013, the WHO declared viral hepatiti...

Rheumatologic manifestations of HIV/AIDS

There has been a decline in the prevalence of HIV/AIDS and a decline in AIDS-associated deaths. However, the World Health Organization estimates that roughly 35 million people are living with HIV. Globally, there are sti...

Rheumatoid arthritis and the concept of autoimmune disease

We critically review the concept of autoimmunity in Rheumatoid Arthritis (RA). To classify a disease as autoimmune, it is necessary to demonstrate that the immune response to a self-antigen causes the observed pathology....

Download PDF file
  • EP ID EP604794
  • DOI -
  • Views 64
  • Downloads 0

How To Cite

Federica Canzano, Alessia Paganelli, Paola Volpe, Roberto Paganelli (2018). The role of miRNAs in autoimmune inflammatory diseases. International Journal of Clinical Rheumatology, 13(6), 360-363. https://europub.co.uk./articles/-A-604794