THE TRADITIONAL USES AND PHARMACOLOGICAL ACTIVITIES OF MUCUNA PRURIENS (L)DC: A COMPREHENSIVE REVIEW
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2017, Vol 7, Issue
Abstract
Abstract Medicinal plants have served as a constant source of medicaments, which have a great efficacy and demand for the treatment of various diseases. One of the plants, that deserve attention is Mucuna pruriens. The present review was designed to evaluate the preliminary phytochemical screening and secondary metabolites. Mucuna pruriens (L.) DC belongs to the family Fabaceae and is commonly known as Velvet bean, Cow witch, Cow hage due to morphology, phytochemical constituents, traditional uses, medicinal values and some pharmacological activities. Different parts of the plant are used in Ayurvedic research since ancient period due to their excellent medicinal values and cure many diseases such as bone fractures, cough, dog-bite, madness, pain, pleuritis, ring worm, scorpion sting, snake-bite, sores and syphilis, and is anticholestrolemic, antiparkinson, antidiabetic, aphrodisiac, anti-inflammatory and antimicrobial, it is also used for the treatment of menstruation disorders, constipation, edema, fever, tuberculosis, etc. The seeds of Mucuna pruriens contain alkaloids, glycosides, reducing sugars, saponins, tannins, terpenoids, calcium, phosphorus and potassium, polyphenolic substances, protease inhibitor, phytic acid, and L-dopa is a major constituent present in whole herb. M.pruriens alkaloid P, Q, R, S, X (Alkaloid-misc), Myristic acid, Niacin (Inorganic), N,N1 Dimethyltryptamine, N,N1-Dimethyltryptamine-n-oxide, Nicotine, Oleic acid, Palmitic acid, Palmitoleic acid (Lipid), Phenylalanine, Phosphorus (Inorganic), Polysaccharide, Proline, Protein , Prurienidine, Prurieninine (Alkaloid-misc), etc are available. The most important of these bioactive compounds of plants are secondary metabolites. The present review is an attempt to provide reported details of information on this herb and its phytoconstituents and pharmacological activities. It is an attempt to provide a direction for further research.
Authors and Affiliations
B. J. Divya. , B. Suman. , M. Venkataswamy, K. ThyagaRaju*
Keywords
Related Articles
- EP ID EP330518
- DOI -
- Views 119
- Downloads 0
BIOSYNTHESIS OF SILVER NANOPARTICLES AND CHARACTERIZATION
Abstract In current science, nanotechnology has been thriving at a tremendous rate in all aspect of Science and Technology. It deals with between 1 to100 nm sizes of nanoparticles in at least one dimension and involves i...
Development and Validation of Spectroscopic Method for Simultaneous Estimation of Acebrophylline and Montelukast Sodium in Combined Dosage Form
A novel combination of Acebrophylline and Montelukast Sodium is used in the treatment of chronic obstructive pulmonary disease (COPD) and bronchial asthma. A simple, sensitive, accurate and reproducible spectroscopic met...
COMPARATIVE STUDY AND ANALYSIS OF RELEASE KINETICS OF CORIANDER FORMULATIONS
Acne is an inflammatory disease of sebaceous follicles of skin. The present study was conducted to formulate and evaluate the topical anti acne formulation of coriander oil and coriander aqueous extract with and without...
FORMULATION AND CHARACTERIZATION OF TRANSDERMAL FILMS OF TORASEMIDE
The purpose of this research was to develop a matrix-type transdermal therapeutic system containing drug Aceclofenac with different ratios of hydrophilic (hydroxyl propyl cellulose) and hydrophobic (ethyl cellulose) poly...
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF CIPROFLOXACIN HYDROCHLORIDE AND FLUOCINOLONE ACETONIDE IN THEIR SYNTHETIC MIXTURE
Abstract The present research work aims to develop a simple, precise, accurate, rapid, reproducible and economical method for the estimation of Fluocinolone acetonide and Ciprofloxacin hydrochloride in their synthetic mi...