The Use of Fibrin Sealant in Chiari Malformation Type-1 Surgery; Is It Effective in Preventing the Formation of CSF Fistula?
Journal Title: THE ULUTAS MEDICAL JOURNAL - Year 2019, Vol 5, Issue 1
Abstract
Background: Symptomatic disease requires surgical intervention comprising of posterior fossa decompression with or without an expansile duraplasty. Until date, the optimal surgical treatment for CM-1 has not been delineated. Thus, we evaluated the results to assess the effectiveness of fibrin sealant augmentation in combination with locally harvested autologous pericranium for duraplasty in adult CM-1 decompression. Materials and Methods: We retrospectively evaluated the cases that were operated due to CM-1. The cases were divided into two groups in which fibrin sealant (FS) was used and not used. There were 15 patients in the first group (FS group) and 16 in the second group (no fibrin sealant (NFS) group). We followed the standardized surgical technique suggested by Stevens and colleagues for CM 1 decompression. Results: Cerebrospinal fluid (CSF) fistula was not observed in any patient in the FS group. However, in the NFS group, two patients were reported to develop CSF fistula. Although the findings are not statistically significant, these are clinically important. Conclusion: Use of FS to seal the autologous graft during closure may prevent the occurrence of CSF fistula among patients of CM-1.
Authors and Affiliations
Huseyin Dogu, Abdurrahman Avar Ozdemir
Keywords
Related Articles
- EP ID EP609213
- DOI 10.5455/umj.20191108075317
- Views 126
- Downloads 0
Correlation of Maternal and Cord Blood Leptin Concentrations with Neonatal Birth Weight in Term, Preterm and Growth-Restricted Fetuses
Background: To determine the association of cord blood and maternal leptin levels with neonatal birth weight in preterm deliveries, intrauterine growth-retarded neonates, and term neonates. Materials and Methods: Sixty p...
Is There Any Relationship Between Circulating Serum 25-Hydroxyvitamin D Level and Presence of Helicobacter Pylori As Well As Gastric Inflammation Severity?
Background: Helicobacter Pylori (H. Pylori) and ongoing chronic gastric inflammation are the most crucial factors leading to gastric cancer. The serum 25 Hydroxyvitamin D is the fundamental keys to the proper functioning...
The Effectiveness of Ganciclovir Comparing with Combination Therapy of Oxytetracycline HCI and Polymyxin B Sulfate in Herpetic Epithelial Keratitis
Introduction: Herpes simplex virus is a common keratitis agent. There are two different types of virus, type 1 and 2. Type 1 shows three main clinical pictures in the cornea: epithelial herpetic keratitis, stromal kerati...
The Effect of Delivery Mode on the Female Sexual Function Index
Background: Sexual function is one of the parameters affecting female life and life quality. We aimed to examine the effect of delivery mode on female sexual functions. Materials and methods: Female sexual function in...
Arrested Pneumatization of the Sphenoid Sinus: A Normal Variant That Can Be Confused With a Pathological Entity
Background: An arrested pneumatization of the sphenoid sinus is an anatomical variant. It is known that the sphenoid bones undergo early fatty marrow conversion antecedent to normal pneumatization. Since it is a developm...