Therapeutic effect evaluation of autologous platelet-rich plasma in the treatment of patellofemoral osteoarthritis based on MOCART 2.0 knee score system
Journal Title: Chinese Journal of Blood Transfusion - Year 2024, Vol 37, Issue 9
Abstract
Objective To explore the therapeutic effect of autologous platelet-rich plasma (PRP) in the treatment of patellofemoral osteoarthritis (PFOA) based on the Magnetic Resonance Observation of Cartilage Repair Tissue 2.0 (MOCART 2.0) knee score system. Methods A total of 22 patients (28 knees) with PFOA treated by intraarticular PRP injection in our hospital from January 2020 to December 2023 were enrolled in the study. The nuclear magnetic resonance(NMR) images before and after treatment were compared using the MOCART 2.0 knee score system. Visual Analog Scales (VAS) score and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score before and after treatment were evaluated and compared, and adverse reactions were observed during the treatment. Results The MOCART 2.0 knee score showed no difference before and after treatment (53.4±12.2 vs 49.9±2.1)(P>0.05). In the subgroup analysis, the "signal intensity of the repair tissue" score and the "subchondral changes" score were better than those before treatment as(5.5±1.5)vs(4.6±1.5)and(15.9±4.3)vs(13.2±6.4)(P<0.05). There were no significant changes in indicators as " degree of cartilage filling" , " integration with adjacent cartilage edges" , " repair of tissue surface structure" , " repair of tissue structure" and " bone changes" (P>0.05).The VAS score and WOMAC score gradually decreased at 1 month, 3 months and 6 months after treatment and were better than before treatment (P<0.05). Incidence of adverse reactions was 4% (4/112). Conclusion Intraarticular PRP injection is an effective and safe option for treatment of PFOA, and can improve the cartilage signal intensity and alleviating subchondral bone edema.
Authors and Affiliations
Zefeng SHI, Kongxi ZHAO, Ruixian LUO, Ke SUN
Keywords
Related Articles
- EP ID EP748042
- DOI 10.13303/j.cjbt.issn.1004549x.2024.09.003
- Views 54
- Downloads 0
Study on the ratio of blood transfusion components in disseminated intravascular coagulation caused by sever postpartum hemorrhage
Objective To investigate the transfusion ratio of plasma to RBC suspension during DIC caused by sever postpartum hemorrhage, so as to improve the clinical blood transfusion protocol. Methods A total of 82 parturients, wh...
Autologous blood transfusion during heart valve replacement surgery: a retrospective study
Objective To retrospectively analyze the indexes of autologous blood transfusion during heart valve replacement, in order to provide reference for allogeneic blood transfusion during heart valve replacement surgery under...
Study on the production efficiency of platelet components in 24 prefecture-level blood stations in China
Objective To learn the production efficient of platelet components among prefecture-level blood stations in China, to provide supporting data for those blood stations to optimize the production mode of platelet component...
Serological and molecular biological analysis of Aw43 subtype: report of two cases
Objective To conduct serological identification and molecular study of two patients with ABO ambiguous blood group. Methods The serological tests were conducted by the tube method. DNA direct sequencing was performed to...
Current situation of blood donation of ethnic minorities in Pu′er City, 2019~2021.
Objective To investigate the participation of ethnic minorities in voluntary blood donation, so as to provide research basis for understanding and promoting blood donation of local ethnic minorities, and further improve...