Therapeutic tricyclic antidepressant drug monitoring in younger and older depressive patients.
Journal Title: Pharmacological Reports - Year 2006, Vol 58, Issue 4
Abstract
The present study shows the evaluation of clinical state and serum level of tricyclic antidepressants in thirty-eight depressive younger and elderly patients during 8-week observation. We observed no statistically significant differences, neither in psychometric scale scores nor in drug serum levels in both groups of patients.
Authors and Affiliations
Maria Radziwoń-Zaleska, Halina Matsumoto, Michał Skalski, Joanna Wilkowska, Piotr Januszko, Daria Matoszko, Anna Dziklińska, Bartłomiej Gmaj, Waldemar Szelenberger
Mechanisms of platelet-activating factor (PAF)-mediated responses in the lung.
Platelet-activating factor (PAF) is a potent lipid mediator that has been implicated in asthma, sepsis, acute lung injury and ischemia/reperfusion injury. Its actions in the lungs include vasoconstriction, bronchoconstri...
Modulation of chemical signaling: current problems after four decades of research. Symposium on the occasion of the retirement of Professor Manfred Göthert. Bonn [Germany], June 10, 2006.
Interactions between drugs and sulforaphane modulate the drug metabolism enzymatic system.
Background: Sulforaphane (SFN) is a potent chemopreventive agent, which is widely consumed in diet or as a diet supplement. It modulates the enzymes of II and III metabolism phase. In this paper, the influence of SFN and...
Combined treatment with imipramine and metyrapone induces hippocampal and cortical brain-derived neurotrophic factor gene expression in rats.
The problem of drug-resistant depression indicates a strong need for alternative antidepressant therapies. Recently it was shown that joint administration of imipramine (IMI) and metyrapone (MET), an inhibitor of glucoco...
Purinoceptors in renal microvessels: adenosine-activated and cytochrome P450 monooxygenase-derived arachidonate metabolites.
Cytochrome P450 (CYP)-dependent epoxyeicosatrienoic acids (EETs) dilaterat preglomerular microvessels (PGMVs) when adenosine 2A receptors (A(2A)R) are stimulated. As high salt intake increases epoxygenase activity and ad...