Therapy of Primary Hypothyroidism with α-Lipoic Acid Review of Studies Results
Journal Title: Міжнародний ендокринологічний журнал - Year 2016, Vol 4, Issue 76
Abstract
Primary hypothyroidism occurs in the general population with an incidence of 0.5–1 %, and includes congenital and acquired (due to autoimmune thyroiditis, after surgical removal of the thyroid gland or treatment with radioactive iodine) forms. The basic treatment of primary hypothyroidism is replacement therapy with L-thyroxine. Combined administration of L-thyroxine and α-lipoic acid resulted in more marked decrease of oxidative stress, hyperlipidemia, hyperactivity of the immune system, endothelial dysfunction and neurological disorders, observed in patients with primary hypothyroidism, as compared to monotherapy with L-thyroxine. α-lipoic acid use was effective in adults and children, in case of parenteral and/or oral administration.
Authors and Affiliations
Tat'yana Tlustova
Keywords
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