Three Year Resistance Profile of Acinetobacter baumannii and Pseudomonas aeruginosa Strains Isolated from Intensive Care Units
Journal Title: Türk Yoğun Bakım Dergisi - Year 2019, Vol 17, Issue 3
Abstract
Objective: The objective of the study was to investigate the three-year antibiotic susceptibility of Pseudomonas aeruginosa and Acinetobacter baumannii strains isolated from intensive care unit (ICU) specimens and to evaluate the changes in resistance rates. Materials and Methods: The resistance profiles of Pseudomonas aeruginosa and Acinetobacter baumannii strains isolated from ICU specimens between January 2015-2018 were analyzed retrospectively and the annual resistance rates were evaluated. Results: Acinetobacter baumannii was isolated in 609 and Pseudomonas aeruginosa was isolated in 420 of the ICU specimens over a three-year period. Strains were most frequently isolated from general ICU. The three-year mean resistance of Acinetobacter baumannii and Pseudomonas aeruginosa to colistin, amikacin, gentamycin, imipenem, meropenem, ciprofloxacin, ceftazidime, piperacillin / tazobactam was 0.5%, 79%, 86%, 96%, 96%, 97% 98%, 99% and 5%, 21%, 25%, 35%, 38%, 40%, 42%, 45%, 49% and 53%, respectively. The most effective antibiotics were for Acinetobacter baumannii and Pseudomonas aeruginosa were colistin (99.5% vs 95%) and amikacin (21% vs 79%), respectively. Conclusion: It was found that Acinetobacter baumannii strains isolated from ICUs were resistant to many antibiotics and that Pseudomonas aeruginosa isolates were more susceptible. These data are proof that new antibiotics are needed in the treatment of infections caused by Acinetobacter baumannii. It would be appropriate for each hospital to monitor changes in their resistance rates and to update the empirical treatment principles.
Authors and Affiliations
Mediha Uğur, Serpil Genç
Keywords
Related Articles
- EP ID EP619260
- DOI 10.4274/tybd.galenos.2018.94103
- Views 139
- Downloads 0
Amitriptyline Cardiac Toxicity Treated with Hemoperfusion
Tricyclic antidepressant intoxication is frequently encountered among children and adults due to widespread use of the drugs. Amitriptyline is among the major tricyclic antidepressants. It affects the cardiovascular, res...
Icterohemorrhagic Leptospirosis: A Case Report
Leptospirosis is a zoonotic infection caused by spirochetes and is usually seen in rural areas. The clinical status may range from self-limiting mild leptospirosis to icterohemorrhagic leptospirosis characterized by jaun...
Microbiota and Intensive Care
It is estimated that there are a total of 1014 microorganisms colonized in many organs and tissues in the human body. It is also estimated that there are trillions of bacteria in the human body, almost 10 times that of h...
The Effect of Progressive Muscle Relaxation Exercises After Endotracheal Extubation on Vital Signs and Anxiety Level in Open Heart Surgery Patients
Objective: The purpose of this study was to examine the effects of the exercises of progressive muscle relaxation (PMR) on vital signs and anxiety level after endotracheal extubation in open heart surgery. Materials and...
Bilateral Pneumothorax during Apnea Test: A Case Report and Literature Review
Brain death is characterized by irreversible loss of all brain functions and it is defined as a clinical condition where intracranial circulation stops. Apnea test is one of the tests which is used in the clinical diagno...