Thrombolytic Use During Cardiopulmonary Arrest in Massive Pulmonary Embolism: Return to Life of Two Patients
Journal Title: Turkish Journal of Intensive Care - Year 2019, Vol 17, Issue 2
Abstract
The diagnosis of pulmonary embolism is still difficult, because it may occur with different symptoms and signs. These cases can be admitted to the emergency department with shock, syncope or cardiopulmonary arrest. More than 70 percent of cardiopulmonary arrest cases are caused by acute myocardial infarction or massive pulmonary embolism and it has a poor prognosis. We present two cases of massive pulmonary embolism requiring cardiopulmonary resuscitation and administered thrombolytic agents. Two patients received 10 mg bolus of recombinant tissue-type plasminogen activator (alteplase) followed by 90 mg intravenous infusion for two hours. Rapid clinical and hemodynamic improvement occurred after thrombolytic injection and the patients were discharged from the hospital. In case of suspicion of massive pulmonary embolism in cardiopulmonary arrest cases, thrombolytic agents should be administered during cardiopulmonary resuscitation. This procedure will treat the condition caused by arrest and also is shown to have beneficial effects on the early microcirculatory cerebral reperfusion and to prevent neurological sequelae.
Authors and Affiliations
Dursun Alizoroğlu, Ahmet Emin Erbaycu, Pınar Çimen, Özlem Ediboğlu, Cenk Kıraklı
Keywords
Related Articles
- EP ID EP48749
- DOI 10.4274/tybd.galenos.2018.30974
- Views 288
- Downloads 0
Prolonged Stay in Intensive Care Unit: Retrospective Analysis of Predisposing Factors and Outcome
Objective: Prolonged stay in the intensive care unit (ICU) is a serious problem resulting in increased cost, resource utilization, and morbidity and mortality. This study was aimed to discuss the factors affecting the pr...
Evidence-based Practices in the Prevention of Central Venous Catheter Infections: Knowledge of Intensive Care Nurses
Objective: This study aimed to determine the knowledge level of intensive care nurses regarding evidence-based practices in the prevention of infections related to the Central Venous Catheter (CVC). Materials and Method...
Evaluation of Microorganisms and Antibiotic Resistance Profile Isolated in Intensive Care Unit Patients
Objective: Proper surveillance administered by infection control committee members may reduce infection rates and antibiotic use in intensive care units. This study aimed to evaluate the results of blood, respiratory and...
The Effect of Central Venous Catheter Care on Infection Development: A Systematic Review
Objective: This study was carried out systematically in order to determine the effect of central venous catheter care on central venous catheter-related infection. Materials and Methods: In this systematic review, resea...
Evaluation of Patients with Brain Death Diagnosis and Investigation of the Effect of New Regulation on the Duration of Diagnosis
Objective: Today, the number of patients waiting for organ transplantation is increasing. The detection of brain death in a cadaveric donor is valuable and should be performed quickly. In 2014, Turkish Ministry of Health...