Thyroid Profile in Premature Canities: A Study of 216 Patients
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 3
Abstract
Introduction: Premature canities or premature graying of hair is an important cause of low self-esteem with significant adverse effects on the appearance and socio-cultural adjustment and acceptance, and thus is a common cause of referrals to the dermatology clinics. Despite extensive research being carried out, its pathogenesis is still poorly understood. Its association with certain organ specific autoimmune diseases including those of thyroid has been observed. The purpose of this study was to evaluate the role of thyroid gland in pathogenesis of premature canities. Material and Methods: This study was a cross-sectional, observational, hospital based study conducted on patients of premature canities of age less than 25 years, over a period of eighteen months. Patients were evaluated fully using complete history and routine investigations including thyroid profile. Family history of thyroid disorders was also looked and investigated into. Results: A total of 216 patients were enrolled, with the mean age of presentation being 17.2 ±2.3 years and that of onset being 15.4 ±1.8 years. Females predominated the study(1:1.45). Derangement of thyroid profile was observed in 70 (32.40%) of the cases themselves and first degree family members of 136 (62.96%) cases. Conclusion: This study highlights the importance of periodic and regular thyroid profile screening in patients of premature canities. Whether, early detection and correction of its disorders can prevent progression of premature graying, needs further evaluation.
Authors and Affiliations
Sheikh Manzoor, Seema Qayoom, Samia Aleem, Suhail Raheem Rather, Syed Shahab ud din Bukhari, Farah Sameem
Keywords
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