Thyroid Profile Status of Female Patients with Polycystic Ovary Syndrome (PCOS) in Western Rajasthan
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 2
Abstract
Background: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in women with 6-7% prevalence in the world. PCOS produces symptoms in approximately 5% to 10% of women of reproductive age (12–45 years old). The heterogeneous disorder is associated with menstrual irregularities, hyperandrogenemia, obesity, increased insulin levels and insulin resistance. PCOS together with thyroid disorder create independent risks of ovarian malfunction as well as pregnancy associated problem. An abnormal thyroid concentration could trigger alterations in ovulation and then menstruation. Objective: Assessment of serum Thyroid profile Levels in Female patients with Polycystic ovarian syndrome (PCOS) trying to find a correlation between Polycystic ovarian syndrome (PCOS) and the metabolic functions of Thyroid gland, as well as pregnancy associated problem. Patients and Methods: 50 females were included in this study, they were divided into 2 groups, the first group included 25 PCOS female patients of age group (18-30yr) attending the Out Patient Department, Department of Obstetrics and Gynecology, Dr. S.N. Medical College and its associated group of hospitals, Jodhpur. The result will be compared with the second group in which age matched 25 healthy- control female subjects were included. Patients and controls were subjected to fill history taking, duration of the disease, the clinical course and any complications in relation to the disease were noted, measurement of body mass index and assessment of Serum thyroid hormones and Serum TSH level which was measured by using Enzyme Linked Fluorescent Assay Method. Results: PCOS female patients were found with elevated Serum TSH level and Mean serum TSH values were highly significant as compared to healthy control subjects. While Serum T3 and Serum T4 levels were almost similar in both groups and there was a non-significant relationship. Conclusion: The subclinical higher level of thyroid stimulating hormone in PCOS female patients may be associated with the development of the disease and may also implicated with other symptoms of the disease. As there is high prevalence of thyroid disorders in PCOS patients, thus all women in their reproductive age with and without PCOS, should have their thyroid function tests evaluated.
Authors and Affiliations
Dhamija Shilpa, Kumar Rohitash, Mathur Ranjana
Keywords
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- EP ID EP543827
- DOI 10.21276/ijmrp.2017.3.2.025
- Views 86
- Downloads 0
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