To Assess the Relative Incidence of and to Compare the Hemocytological Changes in Malaria, Dengue and Typhoid Fever or Their Combination, in Children Admitted in A Tertiary Care Centre in Western UP, India
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 3
Abstract
Introduction: There is a high incidence of acute febrile illnesses such as dengue fever, malaria and typhoid in Western UP, especially during the post rainy season months.. This study aims to assess the relative incidence and to compare the hemocytological parameters associated with these conditions. Materials and Methods: This was the cross-sectional, prospective observational study conducted among paediatric patients admitted to a tertiary care centre in northern India. 90 patients admitted with fever of less than 3 weeks and diagnosed with dengue, malaria, typhoid or their combination were included. NS1 antigen or IgM antibodies tests were used to diagnose dengue, Card test for malaria antigen or malarial parasites on a peripheral smear to diagnose malaria and Typhidot/ Widal test to diagnose typhoid. ANOVA and logistic regression analyses were conducted to analyze the hemocytological parameters. Results: Moderate/severe thrombocytopenia was observed with greater frequency among dengue and malaria patients with a greater severity in the latter or when both coexisted. Dengue was more often associated with high haemoglobin and low total leukocyte counts while typhoid was associated with a wide variation in the total leukocyte counts with relatively lower incidence of thrombocytopenia. Predicted probabilities suggested the likelihood of a particular disease given the hemocytological parameters in relation to the patient's age. Conclusion: Incidence of dengue was highest followed by typhoid and malaria. Certain trends in hemocytological parameters emerged that could guide physicians on the most likely disease in the absence of formal confirmatory tests not always available at the primary care setting.
Authors and Affiliations
Ritu Mital, Vikas Agarwal, Amit Agarwal
Keywords
Related Articles
- EP ID EP426947
- DOI -
- Views 93
- Downloads 0
Correction of Acute Sagittal Plane Angular Deformity of Bilateral Tibia in a Case of Osteogenesis Imperfecta using Limb Reconstruction System
Introduction: Osteogenesis imperfecta is a genetic connective tissue disorder characterized by formation of brittle bones prone to develop fractures and deformities of limbs. Correction of deformity and bone union remain...
Study of Clinical Profile and Management of Incisional Hernia
Introduction: Incisional hernia is a serious postoperative complication of surgical intervention. Incisional hernia is diffuse extrusion of peritoneum and abdominal contents through the weak scar of an operation of abdom...
Urinary Tract Infection in Diabetics - A Five Year Retrospective Study on the Prevalence of Bacterial Isolates and its Antibiotic Susceptibility Patterns in A Tertiary Care Hospital in South India
Introduction: Urinary tract infection (UTI) is almost most common seen infection in the diabetic patient due to various local and systemic immunopathogenetic reasons. This causes multiple renal and extrarenal complicatio...
Assessing Asthma Control using Asthma Control Test and Spirometry
Introduction: The goal of asthma treatment is to obtain and maintain a good control of symptoms. The focus of asthma control is now shifting to an assessment and treatment approach. This study aimed at assessing asthma c...
Comparative Assessment of the Effectiveness and Safety of Sertaconazole Cream Versus Terbinafine Cream Versus Luiliconazole Versus Clotrimazolecream in Patients with Tineacruris
Introduction: Dermatophytosis is an infection of keratinized tissues, epidermis and its appendages hair and nails.Topical treatment of dermatophytosis has advantages like targeting the site of infection which minimizes s...