To Study the Changes in Intraocular Pressure during various Steps of General Anesthesia using Thiopentone Sodium or Ketamine for Induction and Succinylcholine for Neuromuscular Blockade

Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 6

Abstract

Background: Several general and local anesthetic techniques have been employed to try and prevent increase in intraocular pressure during surgery. Interest in general anesthesia for intraocular surgery is relatively recent. Many surgeons now prefer full anesthesia and indeed the increasing scope of ophthalmic surgery demands it. This study was therefore undertaken to know the changes in intraocular pressure, during various steps of general anesthesia using thiopentone sodium or ketamine for induction and suxamethonium (succinylcholine) for neuromuscular blockade. Material and Methods: Sixty patients between the age group of 1-75 years were selected for this study. These patients were divided into two groups –I and II. The patients in groups were given general anesthesia and were operated for either ophthalmic or non – ophthalmic indications. A detailed general examination (including measurement of blood pressure) and systemic examination was done to rule out any systemic disorder which would directly or indirectly affect the measurement of intraocular pressure during the course of the study. Routine blood and urine investigations were done. Results: The mean fall in intraocular pressure after induction as compared to mean baseline intraocular pressure was 2.48±1.32 in group – I. The mean rise in intraocular pressure after induction as compared to mean baseline intraocular pressure was 2.67±2.08 in group-II. This difference in the intraocular pressure after induction in group -I was statistically highly significant as compared to group -II (p<0.01). Conclusions: Thiopentone sodium can be safely used as an inducing agent in any intraocular surgery done under general anesthesia. Ketamine, as far as possible, should be restricted to extraocular ophthalmic surgeries.

Authors and Affiliations

Manjiri V. Deshpande

Keywords

Related Articles

Modified Combined Spinal and Epidural Analgesia with Buprenorphine and Bupivacaine

Context: Combined spinal and epidural analgesia is performed by double space or single space technique. It can also be performed through single intervertebral space with a CSE needle or a Spinal needle which is the modif...

Comparative Evaluation of Different Local Anaesthetics in Supraclavicular Brachial Plexus Block in Pediatric Patients

Introduction: Peripheral neural blockade remains a well-accepted component of comprehensive anaesthetic care in adults, but nowadays it is gaining popularity for children also. This study aims toevaluate the onset, durat...

Crystalloid Preload Versus Crystalloid Co-load During Elective Caesarean Section Under Spinal Anesthesia

Background and Aim: Spinal anesthesia is a preferred technique of anesthesia for pregnant women undergoing caesarean section. The major disadvantage with this technique is maternal hypotension which carries the greatest...

Oral Premedication in Paediatric Surgeries under General Anaesthesia with Ketamine versus Midazolam: A Comparative Study

Background: Pre-operative anxiety (anxiety regarding impending surgical experience) in children is a common phenomenon that has been associated with a number of negative behaviors during the surgical experience (e.g. agi...

Comparison of Intrathecal Adjuvants with Levobupivacaine in Lower Limb Surgeries

Background and Aim: Studies and research are ongoing to find appropriate adjuvants tointrathecal local anaesthetic agents to make them more effective and economical. In view of the same we undertook a study with Levobupi...

Download PDF file
  • EP ID EP541346
  • DOI 10.21088/ijaa.2349.8471.5618.15
  • Views 100
  • Downloads 0

How To Cite

Manjiri V. Deshpande (2018). To Study the Changes in Intraocular Pressure during various Steps of General Anesthesia using Thiopentone Sodium or Ketamine for Induction and Succinylcholine for Neuromuscular Blockade. Indian Journal of Anesthesia and Analgesia, 5(6), 969-976. https://europub.co.uk./articles/-A-541346