To Uncover Various Factors Associated with Positive Blood Cultures amongst Neonates and Children- A Prospective Hospital based Study
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 4
Abstract
Introduction: Septicemia is a serious bloodstream infection. Neonatal sepsis is a clinical syndrome characterized by signs and symptoms of infection with or without accompanying bacteremia in the first month of life. Neonatal infections currently cause 1.6 million deaths annually in developing countries. Sepsis and meningitis are responsible for most of these deaths. The aim of the present retrospective study was to uncover various factors associated with positive blood cultures amongst neonates and children. Material and methods: The present study was a hospital based prospective study conducted by the department of paediatric and microbiology in the institute. Only clinically suspected cases of blood stream infections amongst high risk neonates and children were in this 6 month prospective study. A detailed history including age, sex, socio- economic status, distribution of lesion and duration of illness and any associated risk factors contributing for the illness was elicited from the patients. Blood sample was collected and processed. The categorical data were analyzed by calculating proportion. The Chi Square test was used to see the association among categorical variables. Result: Out of the 80 subjects who were enrolled in this study, there were 48 males and 32 females. out of 80 subjects, 39 subjects belonged to middle class whose score was between the range of 11-15, 33 subjects had score ≤5 belonged to lower class and only 08 subjects belonged to upper class and their score was 16-25. Febrile, per vaginal leaking more than 48 hours and total leucocytes count more than 11000/cumm factors were found to be significantly associated with culture positivity. Conclusion: Sepsis is the leading cause of death and as we know that no single factor is responsible for neonatal sepsis. According to our present study, febrile, per vaginal leaking more than 48 hours and total leucocytes count more than 11000/cumm factors were found to be significantly associated with culture positivity.
Authors and Affiliations
Aditya Mishra, Abhishek Jaiswal, L Agarwal, Rajesh Yadav
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