Tooth Agenesis; Aetiological Factors
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Tooth agenesis is the most prevalent craniofacial congenital anomaly in humans. The term refers to an isolated disorder in the absence of non-dental phenotypes but is also used to describe the manifestation of missing teeth in syndromes. The affected individuals suffer from compromised masticatory functions and have decreased quality of life. Discerning the genetic etiology of tooth agenesis not only improves our understanding of normal tooth development but also provides a fundamental basis for developing potential therapeutic strategies for this anomaly. To date, MSX1, Pax9, Axin2, Eda, And Wnt10a have been established as candidate genes associated with non-syndromic tooth agenesis.This article reviews the recently discovered genes involved in dental agenesis , and provides an update on the aetiological factors underlying this common malformation.
Authors and Affiliations
Abdulgani Azzaldeen, Nezar Watted, Péter Borbély, Muhamad Abu-Hussein
Keywords
Related Articles
- EP ID EP589323
- DOI 10.9790/0853-1601057585
- Views 62
- Downloads 0
Vitamin D Supplementation For Non Specific Musculoskeletal Pain Among Adults Attending Department Of Orthopaedics, Gauhati Medical College: A Randomized Controlled Study
Objectives: The objective of this study was to measure the level of vitamin D in adult patients coming with nonspecific musculoskeletal pain and evaluate the effect of the correction of vitamin D deficiency on the pain,...
Headache: An Out Patients Clinic Approach (Ophthalmological View)
Purpose: The aims of this study were: (i) to estimate the prevalence of headache disorders in patients attending the eye OPD; (ii) to evaluate various causes of headache with special reference to ophthalmic condition; an...
Adhesion of Epoxy Resin Based Endodontic Sealers to the Root Canal with and Without Smear Layer Removal
To study the adhesion of epoxy resin based endodontic sealers by determining the tensile bond strength and evaluating the effect of smear layer removal on the adhesion of the endodontic sealers. Root canals of freshly ex...
Toxic Megacolon with Perforation and Hemolytic Uremic Syndrome with Acute Renal failure in a child due to E Coli
Toxic megacolon is a lethal and potentiallylife threatening condition characterized by dilatation of the colon1.One of the dreaded and rarely encountered consequence of Toxic megacolon is perforation.Toxic megacolon and...
Role of High TENS In Physiatric Management of Primary OA Knee?
Objectives:To evaluate whether High TENS can control pain and subsequently improving tenderness, walk time in OA Knee. Study Design – Prospective randomized controlled parallel group study. Study Area – Osteoarthritis Cl...