Total serum IgE levels in soil-transmitted helminth infected children with atopy symptoms
Journal Title: Paediatrica Indonesiana - Year 2014, Vol 54, Issue 3
Abstract
Background High total serum immunoglobulin E (IgE) levelsand eosinophilia are markers for atopy, but other factors mayalso play a key role in affecting atopy, such as intestinal parasiticinfection. Helminthiasis has been associated with a reduced riskof atopy and asthma symptoms in areas with high prevalence ofparasitic infections.Objective To assess for associations between total serum IgElevel and soil-transmitted helminthiasis (STH) infection, as wellas between STH infection and allergy symptoms.Methods We conducted a cross-sectional stu dy on 84consecutively-enrolled children , aged 7- 13 years, in theSecanggang Subdistrict, Langkat District, North SumateraProvince. Subjects were enrolled into one of two groups, with orwithout STH infection. Total serum IgE measurements and stoolSTH examinations were performed in all subjects. Data on atopyor allergy symptoms were obtained by parental interview.Results The 42 subjects with STH infection had significantlyhigher mean total serum lg E levels than the 42 subjects withoutinfec tion, 1,13 1.26 IU/mL and 744.76 IU/mL, respectiv ely(P = 0.029). We also fo und significant positive association sbetween STH infection and asthma symptoms (P= 0.049), as wellas eczema symptoms (P=0.044).Conclusion Mean total serum IgE level is higher in STHinfectedsubjects than in those without infection. In addition,STH infection is positively associated with asthma and eczemasymptoms.
Authors and Affiliations
Hendri Wijaya, Lily Irsa, Supriatmo Supriatmo, Sjabaroeddin Loebis, Rita Evalina
Keywords
Related Articles
- EP ID EP458720
- DOI 10.14238/pi54.3.2014.149-54
- Views 68
- Downloads 0
Effectiveness of ferric sodium edentate supplementation in children with lead poisoning
Background Lead is a harmful toxin that affects human health worldwide, especially in children. Lead poisoning remains a global problem both in developed and developing countries. The Centers for Disease Control and Prev...
Effect of phototherapy with alumunium foil reflectors on neonatal hyperbilirubinemia
Background Neonatal hyperbilirubinemia (NH) is one of the most common problems in neonates, but it can be treated with blue light phototherapy. Developing countries with limited medical equipment and funds have difficult...
Menstrual cycle patterns of Indonesian adolescents
Background Adolescents often experience menstrual irregularity in the first few years after menarche. Abnormal menstrual cycles may increase the risk of polycystic ovary syndrome. Objective To determine the menstrual cy...
The role of glucomannan fiber in childhood functional constipation
its most common type is functional constipation. The dietary fiber may be useful in childhood functional constipation management, but unfortunately the role of fiber in functional constipation is still less developed.Obj...
Body mass index, atopy, and allergic diseases
Background Prevalence of atopy, allergic diseases, and obesity are increasing. Atopy is an individu and/or familial tendency to sensitization in response to ordinary exposure to allergens. Studies on association of BM I...