Toxicity impact of Silk dye waste effluent induced Histopathological changes in the Stomach and Intestine of Swiss albino mice Mus musculus and their mitigation using Moringa oleifera leaf powder
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 3
Abstract
The results on the effect of oral administration of silk dye waste effluent (2ml/day each animal) on histopathology of the stomach and intestine of swiss albino mice. Revealed sever Histopathological effects in the tissues of both stomach and intestine in Group- II and III but reversible mitigation when using M. oleifera leaves powder at orally fixed dose (300mg/kg/b.w/day) at 30 days and 60 days incubation period. There is marked atrophy of musculature, disintegration of mucosal epithelial cells characterized by cytoplasmic vacuolization, nuclear pycnosis and nuclear fragmentation. A significant damage in Brunner’s gland and crypts of liberkuhn but used of Moringa leafs powder it was significantly recovered the damage tissues has been observed.
Authors and Affiliations
Serina Khatun
Keywords
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