Toxicity Study of Infidol Colic Drop and Sennalax Administered Orally in NMRI Mice
Journal Title: RADS Journal of Pharmacy and Pharmaceutical Sciences - Year 2018, Vol 6, Issue 2
Abstract
Objective: The present study was aimed to investigate preclinical oral toxicity of Infidol colic drop and Sennalax product. Methods: NMRI strains of mice were selected for this study. Animals were divided into two groups i.e. control and treatment group (n=5/sex). Mice were treated orally using gastric gavage with doses (1 or 5 g/kg) of test product i.e. Infidol colic drops and sennalax, for 14 days and observed daily. Result: The present study demonstrated that the infidol colic drops and sennalax is potentially safe with doses of 1000 & 5000 mg/kg, as it does not cause any apparent morbidity and mortality in the animals. Conclusion: The test drug (Infidol colic drop and sennalax) could be safe because it did not show any of the side effects or toxicity on experimental animals.
Authors and Affiliations
Khan Usmanghani
Keywords
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