TRANSABDOMINAL SONOLOGICAL ASSESSMENT OF VAGINAL WALL AND MUCOSAL THICKNESS IN EARLY ADOLESCENT, NEWLY-MARRIED YOUNG ADULT AND POSTMENOPAUSAL SUBJECTS IN SOUTH INDIA- A PRELIMINARY COMPARATIVE STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 70
Abstract
BACKGROUND The vaginal wall like the endometrium of the uterus shows variations in wall thickness in response to oestrogen levels.1,2 Postmenopausal decline in vaginal thickness has been documented in myriad studies.2 Limited published work exists, however, that documents ultrasound assessment of vault thickness.3,4 The aim of the study is to evaluate and compare the vaginal mucosal and wall thickness in postmenarcheal adolescents, newly wed and postmenopausal female subjects by transabdominal sonography. MATERIALS AND METHODS Ultrasound findings of 188 female subjects with regard to vaginal wall and mucosal thickness (VWT and VMT, respectively), who underwent abdominal ultrasonography for trivial abdominal symptoms or as a routine/baseline study over a three month period were analysed. RESULTS A total of 188 female subjects were examined. 48 of these were postmenarcheal adolescents in the 12-15 years age group, 66 were recently wedded young adult subjects in the 20-25 years age group and 74 were postmenopausal females in the 50-75 years age group. Statistically significant differences in VWT and VMT were noted between the three groups. VMT and VVT for postmenarcheal adolescents were 0.8-1.5 mm and 6.2-8.1 mm, respectively. VMT and VVT for recently wedded female subjects were 0.9-2.5 mm and 7.8-21.4 mm, respectively. VMT and VVT for postmenopausal subjects were 0.4-0.8 mm and 4.4-6.8 mm, respectively. CONCLUSION The study suggests that mucosal and wall thickness are maximal in early adult life, minimal in the postmenopausal period and intermediate in early adolescence. A variety of factors are probably responsible, viz. the role of oestrogens and other hormones, vaginal blood flow and mucosal congestion. The variations between wall thickness in young newly-married females and the other two groups suggests that sexual activity has a aetiologic role in the increase in wall and mucosal thickness in this age group.
Authors and Affiliations
Mario Jose Rodriguez
PHARMACOLOGY OF NEWER ANTIMALARIAL DRUGS: REVIEW ARTICLE
Malaria is currently is a major health problem, which has been attributed to wide spread resistance of the anopheles mosquito to the economical insecticides and increasing prevalence of drug resistance to plasmodium falc...
STUDY ON DIAGNOSTIC MODALITIES IN SMEAR NEGATIVE PULMONARY TUBERCULOSIS WITH SPECIAL REFERENCE TO SPUTUM INDUCTION (SI CBNAAT), BRONCHOSCOPY (BAL CBNAAT AND BAL CULTURE)
BACKGROUND Tuberculosis, an important preventable and treatable cause of death is a major health problem worldwide. However, in patients with a compatible clinical picture, sputum smear don’t reveal acid-fast bacilli in...
A COMPARATIVE STUDY OF HAEMODYNAMIC EFFECTS OF INDUCTION DOSES OF PROPOFOL THIOPENTONE AND PROPOFOL KETAMINE COMBINATIONS
BACKGROUND The commonly used intravenous (I.V.) Induction agents in anaesthetic practice are propofol, Thiopentone, Ketamine. But haemodynamic instability is common like use of ketamine results in tachycardia and hyperte...
STUDY OF GRAM-NEGATIVE INFECTIONS AND PATTERN OF RESISTANCE TO CARBAPENEMS IN PATIENTS OF CHRONIC KIDNEY DISEASE
BACKGROUND Gram-negative infections are the most common cause of morbidity and mortality among critically-ill immunosuppressed patients especially in CKD. The increasing emergence of multidrug resistance among these pati...
CORRELATIVE STUDY OF BIOCHEMICAL INVESTIGATION AND IMAGE FINDINGS IN LIVER DYSFUNCTION
The study is undertaken to follow the course of liver disease to accurately evaluate the response to treatment and to adjust treatment when necessary. More so in patients with steroid response auto immune Chronic Hepatit...