Triazoles and its pharmacological activities: A Review
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 12
Abstract
Triazole and its derivatives play wide role in drug discovery processes and have considerable chemical significance and biological activities. The triazole derivatives are more than just passive linkers; they readily associate with biological targets, through hydrogen bonding and dipole interactions. In the last years the synthesis of high nitrogen containing heterocyclic nucleus has been attracted to many pharmaceutical industries. Triazole derivatives has a wide range of applications i.e. such as anti-microbial, anti-tumor, anthelmintic, anti-leishmanial, anti-convulsant ,anti-inflammatory, anti-viral, anti-leprotic, anti-depressant, anti-anxiety, antihistamines, antitubercular and analgesic etc. The derivatization of triazole moieties is based on phenomenon of bioisoterism which include replacement of oxygen of oxadiazole nucleus with nitrogen triazole analogue.
Authors and Affiliations
Dr. Prabhakar Kumar Verma
Keywords
Related Articles
- EP ID EP204830
- DOI -
- Views 67
- Downloads 0
A study on cancer and its drugs with their molecular structure and mechanism of action: A Review
Cancer is a fatal disease that severely effects the human population. For treatment of cancer there is lots of demand of anticancerous drugs which every new anticancer drug or combination is evaluated for safety and effi...
Survey on legibility of prescriptions in private and government clinical setups in South India
Prescription is a written instruction by a medical practitioner that authorizes a patient to be issued with a medicine. It is a medico legal document that should be written legibly, accurately and completely in capital l...
Cross linking of calcium ion in alginate produce spherification in molecular gastronomy by pseudoplastic flow
Spherification is a modern cuisine technique that involves creating semi-solid spheres with thin membranes out of liquids. As a result of this, a burst-in-the-mouth effect is achieved with the liquid. Both flavor and tex...
Evaluation of drug use in the Urban Health Centre of tertiary health care using drug use indicators developed by WHO
The aim of the present study is to tackle ever increasing out of pocket health expenditure by the poor people, the Government of India has brought in National Health Mission with many strategies .One of the essential str...
Formulation and in-vitro characterization of lamivudine controlled release tablet
The goal of any drug delivery system should deliver drug at a rate dictated by the needs of the body over a specified period of treatment. In the present work, an attempt has been made to develop controlled release table...