Unusual Coexistence of Giant Cell Tumor and Small Bone Tuberculosis of the Hand - A Case Report
Journal Title: Global Journal of Medical and Clinical Case Reports - Year 2016, Vol 3, Issue 1
Abstract
Background: The coexistence of giant cell tumor (GCT) and metacarpal bone tuberculosis (TB) of the hand has never been described before in the English written literature. We report here a first observation. Case presentation: We report the case of a 49-year-old male who presented with severe pain in his left hand following a blunt trauma. A plain X-ray of the metacarpal bones showed a pathological fracture of the 4th metacarpal bone (diaphysis), and computerized tomography and magnetic resonance imaging studies confirmed the diagnosis of destructive (lytic) lesions. biopsy of the metacarpal lesion revealed a GCT, and tissue cultures were positive for mycobacterium tuberculosis (TB). He was treated by a standard 4-drug protocol of isoniazid, rifampicin, pyrazinamide and ethambutol for 2 months and an additional 6 months of isoniazid and rifampicin. He then underwent excision of the metacarpal lesion, and the pathological examination showed a GCT with cultures negative for TB. Conclusions: The correct diagnosis of this unique combination of pathologies (GCT and metacarpal bone TB) depended on a high index of clinical suspicion, referral to mycobacterial laboratory tests, careful histologic examination of tissue samples and especially radiomorphologic findings.
Authors and Affiliations
Gideon Charach, Itamar Grosskopf, Ronen Shteinvil, Michal Ehrnwald, Hila Nochomovitz, Lior Charach, Ori Rogowski
Keywords
Related Articles
- EP ID EP243667
- DOI 10.17352/2455-5282.000029
- Views 99
- Downloads 0
Vesical Calculi with Utero Cervico Vaginal Prolapse
Vesical calculi are not commonly seen with utero vaginal prolapse. Calculi may be missed unless ultrasonography or X-ray is done. If not diagnosed problems can occur during surgery and post operatively. If vesical calcul...
Differently Abled People and Their Life
Background: Being differently abled is a complex phenomenon and also concept of disability has shifted from individual impairment to social phenomenon. Objective: Present simple review is to get information for planning...
Splenic Tuberculosis - A Rare Case Report
Splenic tuberculosis (splenic TB) is extremely rare. It is likely to be misdiagnosed as carcinoma of spleen, splenic abscess, lymphoma, or others. The misdiagnosis rate is high if there is no tuberculosis history in othe...
Accidental Acute Poisoning of two Children by Paracetamol-Codeine (1000 Mg/60 Mg) Association - A Case Report
Paracetamol is one of the most used drugs in the world. We report here two cases of children poisoning (less than 3 years old) who were accidentally administered an adult form of rectal suppository containing a combinati...
Spontaneous Rupture of the Kidney Due to Acute Lymphoblastic Leukemia: The First Episode and a Glance on the Literature
Spontaneous rupture of the kidney consists of the atraumatic disruption of the renal parenchyma, followed by hemorrhage or leakage of urine into the perinephric space. A17 years old male known case of Acute Lymphoblastic...