Uric acid levels in metabolically healthy and unhealthy obese patients
Journal Title: Dicle Tıp Dergisi - Year 2014, Vol 41, Issue 4
Abstract
Objective: In this study, we aimed to investigate the difference of uric acid levels between metabolically healthy and unhealthy obese individuals. Methods: Patients of internal medicine and endocrinology outpatient clinics who admitted with the complaint of overweight were separated into two groups, by diagnostic criteria for metabolic syndrome, as metabolically healthy obese and metabolically unhealthy obese individuals. Total of 193 women aged between 18 to 70 years were enrolled into study. Results: Statistically significant differences were determined regarding waist circumference (p=0.038), HOMA-IR (p<0.001) and uric acid levels (p=0.001) between metabolically healthy obese and metabolically unhealthy obese patients while high-sensitive CRP levels (p>0.05) were not differ between these groups. When patients were separated into two groups according to uric acid median, the rate of metabolic syndrome found to be increased in high uric acid group (p=0.021). A correlation analysis showed that uric acid was significantly associated with number of metabolic syndrome parameters (r=0.270, p<0.001) beyond presence of metabolic syndrome. Conclusion: In the fact of determined relation of uric acid with the insulin resistance and significant difference of uric acid levels between metabolically healthy and non-healthy obese groups, uric acid can be considered as a cheap, accessible and sensitive parameter for metabolic syndrome and cardiovascular risk factor in obese individuals. Key words: Uric acid, obesity, metabolic syndrome X
Authors and Affiliations
Emin Akbaş, Adalet Özçiçek, Fatih Özçiçek, Levent Demirtaş, Aysu Timuroglu, Adem Güngör, Nergis Akbaş
Keywords
Related Articles
- EP ID EP132140
- DOI 10.5798/diclemedj.0921.2014.04.0498
- Views 116
- Downloads 0
Liken planuslu hastalarda interlökin-2 ve tümör nekrozis faktör-α seviyelerinin değerlendirilmesi
Amaç: Liken planus T lenfositlerin bazal hücreleri hedef aldığı lenfosit aracılı immünolojik bir hastalıktır. T lenfositlerinden ve keratinositlerden salınan TNF-α’nın apoptozisi indükleyerek liken planusun başlangıç...
The calibration of the percutaneous nephrolithotomy instruments used in pediatric patients with renal stones
Zoledronic acid treatment in an adult patient with Osteogenesis Imperfecta: A case report and review of the literature
Osteogenesis Imperfecta (OI) is a rare heritable condition characterized by bone fragility and reduced bone mass. This pathology is characterized by disruption of biosynthesis of Type I collagen, and production of limite...
Omega-3 yağ asitlerinin sıçan testis dokusu üzerine koruyucu etkileri
Amaç: Bu çalışmada testis dokusu üzerine omega-3 yağ asitlerinin koruyucu etkisi biyokimyasal düzeyde araştırılması amaçlandı. Gereç ve yöntem: Toplam 16 adet Wistar-Albino cinsi erişkin erkek sıçan 2 gruba ayrılarak in...
Goblet hücreli karsinoid: Olgu sunumu
Apendiksin karışık endokrin-ekzokrin karsinomu, ender bir tümör olup, tüm gastrointestinal sistem tümörlerinin çok az bir kısmını oluşturmaktadır. Bu tümörlerin adenokarsinom ve endokrin tümör arasında yer alan interm...