Use of Quantitative Trait Loci (QTL) mapping in breeding
Journal Title: International Journal of Farming and Allied Sciences - Year 2014, Vol 3, Issue 11
Abstract
In breeding programs, because of the time, resources, large quantities of grain required to perform several quality traits analyses, full-scale milling and baking tests are only performed on advanced breeding lines to predict varietal performance. The first published large scale QTL mapping experiments (in yeast and mouse) involved small experimental populations and mostly described the results of genetic mapping. These were soon followed by more focused studies on specific complex traits and aimed at a better understanding of the molecular networks underlying the trait QTLs and experimental validation of inferred candidate genes. QTLs have been identified for quantitative traits as reported in the literature. The number of QTLs detected in a given study depends on different factors, including type and size of mapping population used, trait investigated, the number of environments used for phenotyping, and genome coverage. The QTLs reported in the literature include two groups of genes. The first group constitutes a small proportion of the published literature and includes major genes of very large effects on highly heritable traits, with each explaining a large portion of the total trait variation in a mapping population. The two general goals of QTL mapping in plants are to (a) increase our biological knowledge of the inheritance and genetic architecture of quantitative traits, both within a species and across related species, and (b) identify markers that can be used as indirect selection tools in breeding.
Authors and Affiliations
Saeed rafat, Zahra Aminfar and Baratali Fakheri
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