Usefulness of gamma-glutamyl transpeptidase and mean corpuscular volume in alcoholic liver disease
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction Excessive consumption of alcohol and alcoholism are widely observed risk factors for damage to health and social problems Early identification of alcoholic liver disease could improve the possibility of early treatment and reduce damage to health and health costs Our present study was anticipated to establish the association between the liver enzyme gammaglutamyl transpeptidase and an haematocrit parameter mean corpuscular volume in alcohol liver disease patientsMaterials and Methods Our study includes 100 subjects with 50 cases and 50 controls Serum was collected for the analyses of GGT liver enzymes ALP AST ALT total protein albumin bilirubin Haemoglobin Mean corpuscular volume PCV and RBC were also analyzed The statistical relationship between AST and ALT has been calculated Statistical data analysis was performed by SPSS 20 softwareResults The values of the GGT and MCV levels were significantly increased in patients compared to controls p Conclusion The Overall verdict of this study shows that the increase in GT and MCV levels in ALD patients can be used for added diagnostic markers for the diagnosis of alcoholic liver diseaseKeywords Gamma glutamyl transpeptidase GGT Mean corpuscular volume MCV Alcoholic liver disease ALD
Authors and Affiliations
Muralidhara Krishna C. S, Hemantha Kumara D. S, H L. Vishwanath
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