Using ultra-rapid insulin analogs in children and adolescents with type 1 diabetes mellitus
Journal Title: Міжнародний ендокринологічний журнал - Year 2017, Vol 13, Issue 8
Abstract
Background. The purpose of the study was a retrospective comparative analysis of using insulin analogues of the prolonged and ultra-short action and human genetically engineered insulins of middle and short action in children and adolescents with type 1 diabetes mellitus (DM). Materials and methods. The influence of ultra-rapid insulin analog in comparison with human rapid-action insulin on the course of type 1 DM in 100 children and adolescents was studied. It was applied as basal-bolus regimen of insulin therapy. Analysis of parameters which reflect criteria of insulin therapy effectiveness, positive effect of ultra-rapid insulin analog on the course of DM has been performed. Results. Application of ultra-rapid insulin analog before each meal improved parameters of pre- and postprandial glycemia, decreased the range of fluctuations of blood sugar during the day, reduced and maintained HbA1c level without augmentation of frequency and intensity of hypoglycaemia, and also decreased the level of noctural hypoglycaemia. Conclusions. The ultra-rapid insulin analog is the drug of choice for the effective use in insulin pumps.
Authors and Affiliations
О. V. Bolshova, N. A. Sprinchuk
Keywords
Related Articles
- EP ID EP264349
- DOI 10.22141/2224-0721.13.8.2017.119273
- Views 74
- Downloads 0
Approaches to the correction of indexes of blood lipids and liver functional state in patients with hypothalamic dysfunction
The lecture presents a modern view on etiology, pathogenesis and correction of hypothalamic dysfunction, describes the correlation between hypothalamic dysfunction and liver functional state. The comprehensive method of...
Effective variant of type 2 diabetes mellitus treatment
Background. The purpose was to evaluate the efficiency of phytoextract Ferment S6 as a part of comprehensive therapy in patients with type 2 diabetes mellitus (DM). Materials and methods. Thirty patients with type 2 DM...
Oxidative Stress in Patients with Diabetes Mellitus Type 2 Associated with Exacerbation of Chronic Pyelonephritis
The article presents information on the state of the oxidation-reduction process in exacerbation of chronic pyelonephritis (CP) in patients with diabetes mellitus (DM) type 2. The objective of the study — evaluation of t...
Awareness of General Practitioners Regarding Type 2 Diabetes Mellitus Risk Factors
In this article there are presented the results of an anonymous survey of general practitioners regarding their awareness of risk factors in type 2 diabetes mellitus. The data obtained justify the need to give more atten...
Endothelial Dysfunction and Its Correction in Patients with Essential Hypertension and Type 2 Diabetes Mellitus
The article provides the results of studying the effectiveness of α-lipoic acid impact as a part of complex therapy on endothelial dysfunction in patients with essential hypertension and type 2 diabetes mellitus. There w...