Utility of Haematological Parameters and Reactive Lymphocytes (Virocytes)/Plasmacyatoid Lymphocytes in Peripheral Smear in the Diagnosis of Dengue Fever
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2018, Vol 7, Issue 5
Abstract
Introduction: Dengue fever is the most common Arboviral disease in the world. The four serotypes of dengue virus, 1,2,3 and 4 form an antigenic subgroup of flavivirus. The clinical manifestations of dengue fever range from in apparent to lethal. Various hematological parameters and reactive lymphocytes (Virocytes)/Plasmacyatoid lymphocytes in peripheral smear can help us in the diagnosis of dengue fever. Aim: The aim of the study is to emphasize on the utility of hematological parameters and peripheral smear reactive lymphocytes (virocytes)/plasmacyatoid lymphocytes in the diagnosis of dengue fever. Materials and Methods: A study was carried on a series of patients who attended various health care centres in and around Kurnool for a period of one month. Patients presented with complaints of fever, headache, rash and body pains. Then these patients were tested for dengue, then those positive cases hematological parameters and peripheral smear were analysed. Results: Out of 100 dengue positive cases, 40 cases showed increased hematocrit, 60 cases had leucopenia, 100 cases had thrombocytopenia and 60 cases had relative lymphocytosis. On peripheral smear examination 100 cases showed reactive lymphocytes/ plasmacyatoid lymphocytes. Conclusion: Presence of raised hematocrit, leucopenia, relative lymphocytosis, thrombocytopenia and reactive lymphocytes in peripheral smear helps in the diagnosis of dengue fever.
Authors and Affiliations
B. Shanti Damayanthi
Comparison of Fine Needle Aspiration Cytology & Cell Block in Thyroid Pathology
Context: Accurate preoperative diagnosis of thyroid lesions is imperative and helps surgeons to decide the management of the patients. The differential diagnosis of these nodules includes from non neoplastic to malignant...
Histopathological Pattern Analysis in Non Neoplastic Skin Biopsies: A Prospective Study of 142 Cases
Background: Non neoplastic skin lesions form the majority of morbidity from skin diseases, however majority of them are often diagnosed as non specific dermatitis. The objective of this study was to analyse and classify...
Evaluation of Laboratory Performance of Biochemical Parameters using Sigma Metrics
Introduction : Since the time of Hippocrates the Latin phrase “primum non nocere” i.e. “first, do no harm” has been taught to medical students. In laboratory practice, this is applicable to minimizing error rates,as clin...
Immunohistochemical Expression of P53 and Ki-67 Antigen in Premalignant and Malignant Oral Lesions
Background: p53 protein is a product of TP53 tumor Suppressor gene. TP53 mutations leading to loss of function are the commonest type of genetic damage found in human cancers and oral squamous cell carcinomas, often prec...
Study of Morphological Patterns of Endometrial Curettings in Dysfunctional Uterine Bleeding: A Study of 161 Cases, with Review of Literature
Dysfunctional uterine bleeding is irregular uterine bleeding that occurs in the absence of recognizable pelvic pathology, general medical disease, or pregnancy. Endometrial biopsy is often the first diagnostic tool in a...