Utility of immunohistochemistry in the diagnosis of bone tumors
Journal Title: Journal of Medical and Scientific Research - Year 2014, Vol 2, Issue 2
Abstract
Immunohistochemistry (IHC) plays an important role in the diagnosis of some bone tumors, especially in the differential diagnosis of primary from metastatic non-osseous tumors and in the categorization of small-round-blue-cell tumors. Use of two positive and two negative markers is ideal to improve the specificity. Choice of markers depends upon what tumors are logically within differential diagnosis after seeing the morphology, in correlation with clinical and radiological details provided to the pathologist. Our present article reviews immunomarkers used in bone tumors and their diagnostic significance.
Authors and Affiliations
Sailaja M, Satishrao I
Immunological study of cervical biopsy specimen for human papiloma virus
Background: Cervical cancer is one of the most common cancers among women worldwide and its rates are higher in low and middle income countries. India is one not exemplified from the developing countries. Aims: The main...
Acute small bowel obstruction due to Meckel's diverticulum: An unusual presentation
Majority of the persons with Meckel’s diverticulum are asymptomatic throughout life. In the symptomatic adults, small bowel obstruction is the most common presentation. The common mechanisms of small bowel obstruction in...
Imaging spectrum in Brodie’s abscess
Abstract is not available for this article
Effect of tranexamic acid in perioperative blood loss associated with total knee replacement: Our experience
Introduction: Costs of allogeneic blood transfusions and the associated risks mandate strategies to reduce blood loss in surgery. The objective of this study was to assess the efficacy of anti-fibrinolytic treatment in r...
Early detection of breast cancer - Finding an ‘Indian solution to an Indian problem'
More than one million women worldwide are newly diagnosed with breast cancer annually. Worldwide, a woman dies of breast cancer every minute. In India well over 100, 000 women are newly diagnosed with breast cancer every...