Utility of scrape cytology in early diagnosis of premalignant and malignant oral lesions - A study of 100 cases at a tertiary care centre
Journal Title: Medpulse International Journal of Pathology - Year 2018, Vol 7, Issue 2
Abstract
Background: The oral squamous cell carcinoma [OSCC] is the most common cancer worldwide and constitutes a major health problem in developing countries, representing the leading cause of death. In India it accounts for almost 40% of all cancers. A significant proportion of OSCC develops from premalignant lesions such as leukoplakia, erythroplakia and oral sub mucous fibrosis (OSMF). The histopathological examination of tissue remains the gold standard, but it is an invasive technique with surgical implication. Therefore, the search for the development of newer diagnostic methods were going on, and it led to the discovery of newer molecular methods as well as exfoliative cytology. Molecular methods are costly enough but Exfoliative cytology of oral cavity is a safe, simple, non-invasive and inexpensive method for the diagnosis of premalignant and malignant lesions of oral cavity. Aims/ objectives: For early detection of premalignant and malignant oral lesions, as well as screening of high risk groups. Material and methods:100 cases were included with suspected lesions, high risk groups and healthy subjects as a control. Oral scrape from these patients were collected by brush, smears prepared on slide, fixed with alcohol and stained by PAP and HandE. Results: Out of 100 patients; 24 cases were of healthy individuals [as control], 20 cases were of inflammatory lesions,47 cases were of premalignant lesion and 9 cases were of malignancy (OSCC). Conclusion: Oral scrape cytology is a rapid, painless, safe, inexpensive method for screening and diagnosing a large number of patients in a short time and can be used in camps also for mass screening of populations.
Authors and Affiliations
Neeru Dave, Hiral Chauhan
Keywords
Related Articles
- EP ID EP413989
- DOI -
- Views 78
- Downloads 0
Diagnostic accuracy of fine-needle aspiration cytology in thyroid lesions on basis of its correlation with histopathology in a series of 160 cases
Background:- FNAC is an established, valuable, safe, and expeditetest in the diagnostic management of various thyroid diseases. FNAC is usually the first line of diagnosis in the preoperative decision-making of the thyro...
Diagnostic role of mean platelet volume in cases presenting with thrombocytopenia in a tertiary health care setting of Puducherry
Background: Platelet are membrane bound discoid structure that plays a crucial role in hemostasis. Thrombocytopenia is the reduction in the peripheral blood platelet count below150000 / mm3 after control of preanalytical...
Pathologic and radiologic correlation of paediatric renal tumors
Background: The renal tumors affecting infants and young children are distinct from those that arise in older children and adults. In the present study we attempted to compare the radiologic and histopathologic findings...
A cytological study of salivary gland lesions with fine needle aspiration
Background:A mass in the salivary gland region often are a diagnostic challenge. The present study was conducted to study the non-neoplastic and neoplastic lesions of the enlarged salivary glands by FNAC in patients pres...
Study of incidence and clinical profile of thyroid lesions at a tertiary care hospital
Background: Thyroid lesions are fairly common worldwide and commonly encountered in clinical practice. The incidence of thyroid nodules has been on the rise in recent decades, mainly due to the wider use of neck imaging....