Utilization of a biochemical kit for detection of C-reactive protein (CRP) in the saliva of periodontal disease individuals

Journal Title: RSBO - Year 2011, Vol 8, Issue 3

Abstract

Introduction: Periodontal disease (PD) is a chronic inflammatory process that occurs in response to infection from bacteria in dental plaque. PD affects and destroys the periodontal tissues causing teeth loss.It is also associated to systemic diseases. C-reactive protein (CRP) is a protein produced by the liver and released into the blood during the acute phase of inflammation. Therefore, CRP is very used as a marker for inflammation process.Studies on the presence of CRP in the saliva of the subjects with PD do not exist. Objective: The aim of this study was to test a biochemical kit for CRP detection in blood plasma to monitor CRP in saliva of PD subjects. Material and methods: Saliva was collected from 40 individuals, both sexes, from 20-45 years-old, divided into two groups: Test Group – PD subjects (TG; n = 20) and Control Group (CG n = 20), without PD. The following salivary parameters were analysed: buffer capacity (BC), salivary flow (SF), pH, urea, total proteins, and CRP. Results: pH, SF and BC values were considered normal in both groups. The urea concentration was higher in TG (27.4 mg/dl ± 10.03) than CG (22.9 mg/dl ± 8.3). However, the concentration of total proteins was higher in CG (201.2 ± 100 mg/dl) than TG (155.0 ± 95 mg/dl). CRP was detected in 11 PD subjects and in eight subjects without PD. Conclusion: There were no significant differences between the two groups in relation to SF, pH and BC. However, in PD subjects’ saliva, urea values increased and total proteins decreased. The biochemical kit detected CRP in subjects’ saliva of both groups.

Authors and Affiliations

Anaila Baroni, Juliana Marchioro , Maria Torres, Paulo Tomazinho, João Brancher

Keywords

Related Articles

Resistência de união ao microcisalhamento entre compósitos restauradores e cimentos resinosos

Introduction and objective: The techniques of adhesive cementation have been widely used in dental restoration. The purpose of this study was to evaluate the microshear bond strength between restorative composites and re...

 Survey on jaw fractures occurring due to domestic violence against women

 Introduction: Violence against women has become a public health problem, and the dentist is the main responsible for the treatment of their victims, since numerous cases with a high incidence of impaired maxilloman...

Evaluation of cleaning efficacy of a nickel-titanium rotary system, with or without 17% EDTA passive ultrasonic activation: a scanning electron microscopic study

Introduction: The goal of endodontic instrumentation is to promote root canal cleaning and shaping to prepare it for the subsequent three-dimensional filling. Objective: The aim of this study was to evaluate, ex vivo, ro...

Comparative analysis of the superficial roughness of high-density composite resins

Introduction: The success achieved by the use of composite resins in anterior teeth precipitately leads their use in posterior teeth. However, the indiscriminate application of these materials in cavities with several di...

 Evaluation of radiographic waste management in dental offices and radiology clinics of São Luís (MA)

 Introduction: Lack of information continues to lead the professionals of various areas to contribute to environment degradation, and Dentistry is a potential source of contamination through chemical residues result...

Download PDF file
  • EP ID EP113727
  • DOI -
  • Views 172
  • Downloads 0

How To Cite

Anaila Baroni, Juliana Marchioro, Maria Torres, Paulo Tomazinho, João Brancher (2011). Utilization of a biochemical kit for detection of C-reactive protein (CRP) in the saliva of periodontal disease individuals. RSBO, 8(3), 282-286. https://europub.co.uk./articles/-A-113727