UV Method Development and Validation of Eperisone Hydrochloride in Bulk and Tablet Formulation
Journal Title: RADS Journal of Pharmacy and Pharmaceutical Sciences - Year 2017, Vol 5, Issue 4
Abstract
Objective: To develop and validate a UV simple, precise and cost saving method for fast analysis of Eperisone Hydrochloride in Eperisone tablets. Method: The test is developed by using methanol as diluent, performed on UV visible double beam spectrophotometer at range of 200nm-400nm, and found absorbance on maximum wavelength of 260 nm. The test is then validated by using complete parameters of method validation i.e., linearity, precision, selectivity, accuracy, repeatability, robustness, limit of quantitation and detection. The complete procedure is carried out as per United State Pharmacopeia, ICH and WHO guidelines. Results: Calculate individually all parameters of method validation as per standard that should meet the validation criteria. Conclusion: As per above discussion the method is precise and accurate for analysis of Eperisone hydrochloride in Eperisone hydrochloride tablets.
Authors and Affiliations
Saima Saleem
JUW IN THE FORE FRONT OF JOURNALISM
Jinnah University for Women, Karachi, Pakistan has the distinction to initiate and start three journals under the umbrella of Rayazuddin Research & Development Society. These three journals are Journal of Pharmacy and Ph...
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