VARIOUS TECHNIQUES FOR THE MODIFICATION OF STARCH AND THE APPLICATIONS OF ITS DERIVATIVES
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 5
Abstract
Starch is a major carbohydrate easily extractable from various native sources, like potato, maize, corn, wheat, etc, which finds wide application in various food and non food industries. Since time immemorable various attempts are being made in order to modify this highly flexible polymer with an aim to enhance the positive attributes and eliminate the short comings of the native starches. Modifications are generally made by physical methods like osmotic-pressure treatment, deep-freezing and thrashing; chemical methods that primarily include derivatizations such as etherification, esterification and crosslinking, oxidation, cationization and grafting of starch; enzymatic degradation techniques and genetical modifications which involves the transgenic techniques targeting the various enzymes involved in starch biogenesis. All these techniques tends to produce a variety of derivatives with altered physicochemical properties and modified structural attributes of high technological value for instance carboxymethylated starch used as a binding and disintegrating agent. This review summarizes the various methods of starch modification that can be employed to produce a novel molecule with substantial applications in various industries including a large number of advances in pharmaceutical industry along with the future prospectives.
Authors and Affiliations
Neelam Kavlani , Vijay Sharma , Lalit Singh
METHOD DEVELOPMENT AND VALIDATION OF METFORMIN, GLIMEPIRIDE AND PIOGLITAZONE IN TABLET DOSAGE FORM BY RP-HPLC
A rapid RP-HPLC method was developed and validated for simultaneous estimation of metformin, glimepiride and pioglitazone from pharmaceutical dosage forms. A sensitive chromatographic separation was accomplished on C18 c...
SOME ETHNO-MEDICINAL PLANTS USED BY THE NATIVE PRACTITIONERS OF CHANDEL DISTRICT, MANIPUR, INDIA
This article highlights some ethno-medicinal plants used by the traditional practitioners of Naga community in khangshim bio – region of Chandel district for the treatment of various ailments. A field survey revealed num...
FORMULATION AND EVALUATION OF FILM COATED TICLOPIDINE HYDROCHLORIDE IMMEDIATE RELEASE TABLETS
In the present work attempts were made to with an aim to develop pharmaceutically equivalent, stable, cost effective and quality improved formulation of film coated Ticlopidine Hydrochloride immediate release tablets by...
MOIST WOUND HEALING: PERSPECTIVES FROM AYURVEDA
Wounds are a primary affliction. The healing of wounds is a complex mechanism that calls for a multipronged approach. Wounds have been observed to heal faster in a moist atmosphere as compared to a dry environment. Ayurv...
DIURETIC ACTIVITY OF BUTEA MONOSPERMA FLOWERS EXTRACT
Kidney, as excretory organ of our body serves important function of excretion of waste products, regulation of fluid volume and electrolyte content etc. Damage to kidney can lead to severe life threatening complications....