Vitamin D Deficiency: A Novel Biomarker for Cardiovascular Disease.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 6
Abstract
Background: Vitamin D deficiency is prevalent in most parts of the world. The prevalence of vitamin D deficiency in India in urban area 9-11% and in rural area 3-6%.Coronary artery disease is global health problem and consists of variety of heart illness. Vitamin D deficiency may cause cardiovascular events by a variety of possible biological mechanism. Aims & Objectives: To study the role of vitamin D as an emerging risk factor for coronary artery disease. Materials and Methods: The study was carried out in department of Biochemistry, M. G.M. Medical College included 50 patients of coronary artery disease admitted in M.Y.Hospital. The control population comprised of age and sex matched 50 healthy volunteers. Vitamin D was done on ELISA reader and lipid profile estimation was done on fully automated analyzer. The statistical analysis was done by using SPSS software. The results were expressed as Mean ± SD. The Student t-test was carried out for comparison of the data & P value <0.05 was considered statistically significant. Results: The study revealed that vitamin D level was found to be significantly lower in cases as compared to controls. We also observed significant difference in mean to total cholesterol, HDL cholesterol and LDL cholesterol in between cases and control. Conclusion: This study concluded that continues follow up of vitamin D will be helpful for assessment of increased risk of coronary artery disease events beyond the traditional risk factor.
Authors and Affiliations
Dr Sangita Paneri
Keywords
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