Vitamin D Deficiency and its Association with Thyroid Diseases
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 8
Abstract
Introduction: The primary action of Vitamin D is regulation of calcium and phosphorus homeostasis. Recent studies have shown that Vitamin D deficiency is associated with increased risk of diabetes Mellitus, infectious diseases, atherosclerosis and autoimmune condition like autoimmune thyroiditis There has not been any clear research to show the association between hypothyroidism and Vitamin deficiency. The present study was conducted with the prime aim to establish association between thyroid disorder and Vitamin D deficiency. Material and methods: The present study was conducted in the Department, institute, State. The study was conducted for a duration of two year (June, 2016- June, 2017). This cross sectional study enrolled 90 subjects. Under complete aspetic conditions venous blood was withdrawn from anticubital vein. Levels of T3, T4 and TSH were estimated using fluorescence array. To determine the levels of Vitamin D, 25(OH)D was calculated. All the data was arranged in a tabulated form and analyzed using SPSS software. Independent T Test was used for comparison. Results: It was observed that out of 90 subjects, there were 58.8% patients (n=53) who had Vitamin D deficiency i.e. the Vitamin levels were less than 20 ng/ml. There were 73 cases of euthyroid in which the TSH levels were between 0.25-5 U/U/ml. There were 10 cases of subclinical hypothyroid and 7 cases of overt hypothyroidism. The mean levels of Vitamin D in subclinical and overt hypothyroidism were 16.23+/-10.47 and 13.11+/-10.48 ng/ml respectively. There was a significant difference in the level of Vitamin D in all the cases. Conclusion: In present study deficiency of Vitamin D correlates with increase in levels of TSH. There is progressive decrease in level of Vitamin D from subclinical to overt hypothyroidism.
Authors and Affiliations
Swati Sonawane, Sahil Bansal
Keywords
Related Articles
- EP ID EP424808
- DOI -
- Views 117
- Downloads 0
Carbamazepine Induced DRESS Syndrome
Introduction: The DRESS (Drug Reaction with Eosinophlia and Systemic Symptoms) Syndrome, is a rare encountered disease with delayed type hypersensitivity reaction, induced by drugs which accompanied by fever, skin rash,...
CT Anatomy of Paranasal Sinuses – Corelation with Clinical Sinusitis
Introduction: Coronal CT is a wonderful diagnostic tool for detailed evaluation of paranasal sinus anatomy. With the advent of functional endoscopic sinus surgery considerable attention has been directed towards the unde...
Assessment of Efficacy of TEP Hernia Repair in Routine Surgical Practice and its Peri and Postoperative Complications
Introduction: The extraperitoneal laparoscopic hernia repair has various advantages. Lessened postoperative agony, healthy muscle quality, early recuperation, and a little scar are the primary points of interest proffere...
Assessment of Haemoglobin A1c in the Prediction of Risk of Development of Diabetes
Introduction: Diabetes comprises of a group of metabolic diseases manifested by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. For the prevention of diabetic complications, good glyce...
End to End Hand Sewn Cervical Esophago Gastric Anastomosis Versus Semi Mechanical Stapled Anastomosis in Patients Undergoing Esophagectomy - A Retrospective Comparative Study
Introduction: The Anastomotic leak is one of the main cause of morbidity following esophageal resection for carcinoma of the esophagus. We compared end to end hand sewn anastomotic technique with side to side stapled ana...