VITAMIN D3 LEVEL IN TYPE 2 DIABETES MELLITUS AND ITS CORRELATION WITH HbA1c LEVEL- A CROSS-SECTIONAL STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 32
Abstract
BACKGROUND The role of vitamin D in type 2 diabetes is suggested by a seasonal variation in glycaemic control. It was reported in patients with type 2 diabetes being worse in winter, which might be due to hypovitaminosis D as a result of reduced exposure to sunlight. Aims and Objectives- (I) To estimate the plasma vitamin D3 level in type 2 diabetes mellitus. (II) To find out association between vitamin D3 and HbA1c level. (III) Correlation between serum vitamin D3 level and diabetic cardiovascular complications. MATERIALS AND METHODS A cross-sectional study was conducted among 100 type 2 diabetes patients who were selected from medicine ward and diabetes clinic. The descriptive statistics like percentages, mean and median were calculated. The inferential statistics like Chi-square statistics and Spearman’s correlation were performed for analysis of data. RESULTS HbA1c was increased in majority of patients (71.0%). Majority of the respondents were having low vitamin D levels. There was gross scattering of the dots indicating that poor correlation between HbA1c and Vitamin D levels. The Spearman’s Rho was found to be only 0.092 (poor correlation) and this finding was not significant (p= 0.361). There was poor correlation between HbA1c and Vitamin D3 levels and Vitamin D3 level was not correlated with age and hypertension. CONCLUSION The 25-(OH) D3 concentrations were low in 90% of the diabetic patients. There was an inverse association between the serum concentration of 25-(OH) D3 and type 2 diabetes, thereby suggesting a protective role of vitamin D against the development of the disease.
Authors and Affiliations
Gautam Debbarma, Santosh Reang, Taranga Reang
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