ВПЛИВ БЕТА-АДРЕНОБЛОКАТОРІВ ТА ІВАБРАДИНУ НА ВІДДАЛЕНИЙ ПРОГНОЗ У ПАЦІЄНТІВ ЗІ СТАБІЛЬНОЮ СТЕНОКАРДІЄЮ
Journal Title: World Science - Year 2017, Vol 3, Issue 8
Abstract
We are interested in the research of comparative analysis of the effect of performed medication of the stable angina (SА) on the remote prognosis (after 1 year of observation). 90 patients with SA were divided into three groups, depending on the received equal background therapy (aspirin, rosuvastatin, nitrate) of additional drugs: patients of group I - bisoprolol in a dose of 1.25 _ 7.5 mg / day); patients of group II - carvedilol in a dose of 6.25-12.5 mg / day; patients of group III - ivabradine in a dose of 5-15 mg / day. The same frequency of progression of the cardiovascular lethality and cases of unstable angina in the comparison groups were found. The cases of progression of the myocardial infarction and revascularization were much lower with patients who in addition to background therapy were receiving ivabradine. The dependence of the remote prognosis of patients with CC have been established from dependence on patient treatment, age, heart rate, presence of harmful habits, and endothelial dysfunction markers, in particular of endothelin-1 and homocysteine.
Authors and Affiliations
Т. О. Ілащук, І. В. Окіпняк, С. В. Широкова
Keywords
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