Wilms' Tumor in Children: An Experience of SIOP Protocol from Tertiary Centre

Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 9

Abstract

Background: Wilms’ tumor is the commonest renal .tumor. Survival depends on stage and biologic behavior and economic settings. International Society of Pediatric Oncology (SIOP) has laid down protocol for developing country. Methods: Prospective observational study. aged 1-12 year with wilms’ tumor department of Pediatrics IPGMER, Kolkata .from February 2009- August 2012.. All cases are managed according to SIOP 2001protocol. Follow-up for 2 to 4 years Prognosis is noted in terms of local recurrence or metastasis and overall survival. Results: Out of 8 children male 5 and female 3with age of presentation ranging from 3-12 year (median-5 year). Abdominal lump is the main clinical presentation along with hematuria in 2 and hypertension in 1 child. Clinically and histologically 6 of the children was on stage 1 and 2 were on stage 2. . Out of 8 children, 1 child died soon after nephrectomy due to postoperative complications. Remaining 7 children are disease free till date with no evidence of local recurrence or metastasis. Conclusions: SIOP protocol can be used in management of pediatric Wilms' tumor Stage I and II with excellent prognosis in our settings. However more studies are needed to bring SIOP protocol in treatment of Wilms tumor in India or develop own protocol for our country.

Authors and Affiliations

Anirban Chatterjee

Keywords

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  • EP ID EP212347
  • DOI -
  • Views 62
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How To Cite

Anirban Chatterjee (2015). Wilms' Tumor in Children: An Experience of SIOP Protocol from Tertiary Centre. Journal of Medical Science And clinical Research, 3(9), 7437-7442. https://europub.co.uk./articles/-A-212347