Pharmacodynamic Studies to Demonstrate Bioequivalence of Oral Inhalation Products Journal title: The AAPS Journal Authors: Leslie Hendeles, Peter T. Daley-Yates, Robert Hermann, Jan De Backer, Sanjeeva Dissanayake, Stephen... Subject(s): Medicine
In Vitro, Pharmacokinetic, Pharmacodynamic, and Safety Comparisons of Single and Combined Administration of Tiotropium and Salmeterol in COPD Patients Using Different Dry Powder Inhalers Journal title: The AAPS Journal Authors: Stephen T. Horhota, Jan A. van Noord, Cynthia B. Verkleij, Loek J. Bour, Ashish Sharma, Michael Trun... Subject(s): Medicine
Modeling, Simulation, and Translation Framework for the Preclinical Development of Monoclonal Antibodies Journal title: The AAPS Journal Authors: Kenneth T. Luu, Eugenia Kraynov, Bing Kuang, Paolo Vicini, Wei-Zhu Zhong Subject(s): Medicine
Development of a Preclinical PK/PD Model to Assess Antitumor Response of a Sequential Aflibercept and Doxorubicin-Dosing Strategy in Acute Myeloid Leukemia Journal title: The AAPS Journal Authors: Gerald J. Fetterly, Urvi Aras, Deepika Lal, Michael Murphy, Patricia D. Meholick, Eunice S. Wang Subject(s): Medicine
Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy Journal title: The AAPS Journal Authors: Narendra Chirmule, Vibha Jawa, Bernd Meibohm Subject(s): Medicine
Population Pharmacokinetics and Pharmacodynamics of Ribavirin in Patients with Chronic Hepatitis C Genotype 1 Infection Journal title: The AAPS Journal Authors: Runyan Jin, Michael J. Fossler, John G. McHutchison, Charles D. Howell, Thomas C. Dowling Subject(s): Medicine
Pharmacokinetic and Pharmacodynamic Analysis of Hyperthermic Intraperitoneal Oxaliplatin-Induced Neutropenia in Subjects with Peritoneal Carcinomatosis Journal title: The AAPS Journal Authors: Belén Valenzuela, Ricardo Nalda-Molina, Pere Bretcha-Boix, Vanesa Escudero-Ortíz, Ma... Subject(s): Medicine
Evaluation of α2-Integrin Expression as a Biomarker for Tumor Growth Inhibition for the Investigational Integrin Inhibitor E7820 in Preclinical and Clinical Studies Journal title: The AAPS Journal Authors: Ron J. Keizer, Y. Funahashi, T. Semba, J. Wanders, J. H. Beijnen, J. H. M. Schellens, A. D. R. Huite... Subject(s): Medicine
Pharmacodynamic Model of Parathyroid Hormone Modulation by a Negative Allosteric Modulator of the Calcium-Sensing Receptor Journal title: The AAPS Journal Authors: Anson K. Abraham, Tristan S. Maurer, Amit S. Kalgutkar, Xiang Gao, Mei Li, David R. Healy, Donna N.... Subject(s): Medicine
Levy G, Hayes B, “Physiochemical Basis of the Buffered Acetylsalicylic Acid Controversy New Engl. J. Med. 262:1053–1058 (1960)”—The Backstory Journal title: The AAPS Journal Authors: Gerhard Levy Subject(s): Medicine
Pharmacodynamic Model of Sodium–Glucose Transporter 2 (SGLT2) Inhibition: Implications for Quantitative Translational Pharmacology Journal title: The AAPS Journal Authors: Tristan S. Maurer, Avijit Ghosh, Nahor Haddish-Berhane, Aarti Sawant-Basak, Carine M. Boustany-Kari,... Subject(s): Medicine
Bilirubin—A Potential Marker of Drug Exposure in Atazanavir-Based Antiretroviral Therapy Journal title: The AAPS Journal Authors: Dinko Rekić, Oskar Clewe, Daniel Röshammar, Leo Flamholc, Anders Sönnerborg,... Subject(s): Medicine
Comparative Performance of Cell Life Span and Cell Transit Models for Describing Erythropoietic Drug Effects Journal title: The AAPS Journal Authors: Nageshwar R. Budha, Andreas Kovar, Bernd Meibohm Subject(s): Medicine
Holford NHG and Sheiner LB “Understanding the Dose-Effect Relationship-Clinical Application of Pharmacokinetic-Pharmacodynamic Models”, Clin Pharmacokin 6:429–453 (1981)—The Backstory Journal title: The AAPS Journal Authors: Nick Holford Subject(s): Medicine
Comparison of Two Pharmacodynamic Transduction Models for the Analysis of Tumor Therapeutic Responses in Model Systems Journal title: The AAPS Journal Authors: Jun Yang, Donald E. Mager, Robert M. Straubinger Subject(s): Medicine
