A Clinical Study of Left Ventricular Function in Patients with Chronic Obstructive Pulmonary Disease
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 8
Abstract
Background: Chronic obstructive pulmonary disease (COPD) patients usually present with the right ventricular hypertrophy and eventual right side heart failure. Sometimes, disturbance in the left ventricular (LV) function is also observed in COPD patients. The prevalence of the LV diastolic dysfunction in COPD patients using echocardiography parameters varies widely in the literature. Aim of the Study: This study aims to evaluate the LV function in patients with COPD with or without pulmonary hypertension (PH). Materials and Methods: A total of 66 patients with COPD without additional cardiac diseases were grouped as “A” and 22 healthy individuals who were matching with sex and age of Group A were named as Group “B.” Spirometry, standard, and tissue Doppler echocardiography were performed in both groups. The results obtained were analyzed. Observations and Results: Among Group A, 36 had PH. The LV systolic function was similar in both the groups. The LV diastolic function and LV function by myocardial performance index (MPI) were significantly different in different grades of COPD. Patients with COPD and hypertension had significantly higher heart rate, less E-wave peak velocity (measured by DTI) (P < 0.05), less E/A ratio (measured by DTI) (P < 0.01) and E/A ratio (measured by flow), and higher MPI (P < 0.05) than normal pulmonary pressure patients. Conclusion: In patients with progressive COPD, there was the effect on LV diastolic function and LV function by MPI, especially those with PH.
Authors and Affiliations
Tirupati S Rajasekhar
Keywords
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