A CLINICAL STUDY OF PATIENTS PRESENTING WITH ACUTE KIDNEY INJURY AT A TERTIARY CARE HOSPITAL
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 36
Abstract
BACKGROUND AKI is a challenging problem in the tropics in view of the changing burden of the disease, the late presentation of patients to health care facilities and the lack of resources to support patients with established AKI in many regions. The mortality of patients with AKI in the tropics is unacceptably high. The treating physician in rural centers should be competent to treat trivial causes of AKI and refer those individuals who require critical care at the right moment. MATERIALS AND METHODS A prospective study of 100 patients admitted with Acute Kidney Injury (AKI) in S.V.R.R. Government General Hospital attached to Sri Venkateswara Medical College (SVMC) during the period of November 2010 to April 2013. Patients were diagnosed with AKI using RIFLE criteria based on Serum Creatinine estimation by Jaffe method and also estimating urine output and managed conservatively or with Haemodialysis. RESULTS Out of 100 patients presenting with Acute Kidney Injury (AKI), 33% of cases have been attributed to severe sepsis, 20% to gastroenteritis, 14 % to hair-dye poisoning, 8% to malaria, 6% to cardiorenal syndrome, 6% to snake bite, 3% to hepatorenal syndrome, 2% to obstructive uropathy, 2% to crush syndrome, 2% to heat stroke, 1% to obstetric-related caises, and 3% to miscellaneous causes. 55% of cases were managed with haemodialysis whereas 45% of cases were managed conservatively. Out of the 100 patients, 67% patients were discharged, 28% patients died, and 5 patients left against medical advice. Among 28 of patients who have died, severe sepsis (14 patients) was the most common cause attributing to the mortality (50%). CONCLUSION In our study, sepsis was the most common cause contributing to 33% of cases of AKI, with mortality upto 50%. RIFLE criteria may help physicians to be aware of the risk of renal injury and in starting preventive or therapeutic intervention.
Authors and Affiliations
Mahesh Babu N. , Ramachandra Rao I. V, Hareesh M. V. K
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