A COMPARATIVE STUDY ON ANTI DIABETIC ACTIVITY OF CRUDE EXTRACTS OF ENDOPHYTIC FUNGI FROM SEA WEED GRACILARIA CORTICATA
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 12
Abstract
Diabetes, often referred to by doctors as Diabetes mellitus, describes a group of metabolic diseases in which the person has high blood glucose (blood sugar).Insulin is a hormone that is produced by the pancreas.. Inhibition of α-amylase, enzyme that plays a role in digestion of starch and glycogen, is considered a strategy for the treatment of disorders in carbohydrate uptake, such as diabetes. Gracilaria corticata have been used since ancient times as food, fodder, and fertiliser and as source of médicine. Gracilaria corticata. Endophytic fungi are one of the potential natural resources for new ant diabetic compound sources. The aim of the study was to compare anti diabetic activity of crude extracts of Endophytic fungi from Gracilaria corticata against diabetes. Endophytic fungi were isolated from seaweed Gracilaria coricata, characterized and identified based on morphological and biochemical characters. The identified endophytic fungi were tested for invitro antidiabetic activity by alpha amylase inhibition assay, method the higehest percentage of alpha amylase inhibition at the concentration of 500μl of ethanolic extract of A. niger that showed 41.4% followed by penicillium (39%) A.fumigatus (33.4%) Phoma spp (28.9%) and Syncephalastrum racemosum (23.7%) in comparison with acetone crude extracts of Penicillium (25.2%), Phoma spp (24.2%), A.fumigatus (21.3%), Syncephalastrum racemosum (19.4%), A.niger (17.4%).
Authors and Affiliations
R. Anusha
Keywords
Related Articles
- EP ID EP630423
- DOI -
- Views 143
- Downloads 0
DEMOGRAPHIC AND PHENOTYPIC CHARACTERIZATION OF DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS ISOLATED FROM PATIENTS RESIDENT IN RIVERS STATE, NIGERIA
Tuberculosis (TB) remains a leading public health problem worldwide. In Nigeria the burden of TB is high however only a few cases have been reported especially in Rivers State. The aim of this study is to phenotypically...
NANOMEDICINE: APPLICATION OF NANOTECHNOLOGY
This paper highlights the applications of nanotechnology in medicine termed “Nanomedicine”. Advances in nanomedicine centre on diagnosis (invitro and invivo), pharmaceuticals and therapeutics. Nanobiotechnology utilizing...
REVIEW OF KSHARA KALPANA W.S.R TO “RASATARANGINI”
Rasatarangini written by Acharya Shri Sadananda Sharma in 19th is one of the important book in the field of Ayurveda specially in the field of Rasashastra. No separate chapter is available in Rasa Granthas regarding Ksha...
NANOSTRUCTURED LIPID CARRIER: A NOVEL APPROACH
The primary and foremost aim of writing this article is to focus on the importance and benefits of Nanostructured Lipid Carrier loaded drug delivery systems. The drug can be effectively distributed in the body by followi...
SEASONAL DYNAMICS AND ECOLOGICAL FEATURES OF DERMACENTOR BUGS IN SOUTHERN UZBEKISTAN
Live-stock production, one of the leading sectors of the economy in the Republic of Uzbekistan, is of great importance in ensuring the high productivity of agricultural animals in the production of dairy products. From t...