A randomized clinical trial to compare the effectiveness of two different doses of intravenous Nitroglycerine for manual removal of placenta
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 3
Abstract
Introduction After the birth of the baby if the placenta is not expulsed within 30 minutes of the delivery it is termed as retained placenta The incidence of retained placenta is 2 of deliveries worldwide and is an important cause for maternal mortality and morbidity Nitroglycerine NTG is an organic nitrate that relaxes smooth muscles and produces a generalized vasodilatation As it relaxes the smooth muscle it is also used as a uterine relaxant for manual placental removalAims and Objectives To know the efficacy and safety of intravenous NTG in manual removal of placenta and to know the hemodynamic effects during the procedureMaterials and Methods Total number of patients included in this study were 40 Patients were divided in two groups each group having 20 patients each Group 1 patients were administered with 100 microgm of NTG and group 2 patients with 150 microgm of NTG Clinical parameters and complications were studied and compared between the two groups Placenta was observed for separation and graded as easily separated separated with assistance difficult to separate failed to separate The clinical parameters like hypotension tachycardia headache after awakening palpitation after awakening were compared between the two groupsResults In group 1 we observed that placenta was easily separatedin 12 patients 60 separated with assistance in 3 patients 15 difficult to separate in 3 patients 15 and in 2 patients 10 placenta was not separated In group 2 we observed that placenta was easily separated in 14 patients 70 separated with assistance in 2 patients 10 difficult to separate in 2 patients 10 and in 2 patients 10 placenta was not separatedConclusion Intravenous NTG is an effective and safe method for manual removal of placenta with a dose of 100 microgramKeywords Intravenous Nitroglycerinr Retained placenta
Authors and Affiliations
Shivanand L. Karigar, D G. Talikoti, Basavaraj Patil
Keywords
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- EP ID EP476504
- DOI 10.18231/2394-4994.2018.0075
- Views 91
- Downloads 0
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