A REVIEW ON NOVEL ORAL ANTICOAGULANTS
Journal Title: Hygeia:journal for drugs and medicines - Year 2015, Vol 7, Issue 2
Abstract
Plan: This article reveals the significance of novel oral anticoagulants in place of conventional vitamin K antagonists. Vitamin K antagonists were commonly used since 1941 but it has lot of inconveniences. Preface: Anticoagulants are drugs used to reduce the coagulability of blood. Mainly used for the prevention of disorders characterized by abnormal blood clots and emboli. Warfarin, a vitamin K antagonist was the only choice for chronic oral anticoagulation for more than half a century. It requires periodic monitoring of INR, its efficacy and safety depends upon time in the therapeutic range. Outcome: Recently novel oral anticoagulants (NOAC’s) have been introduced, offering similar effectiveness, safety and convenience of vitamin K antagonist not requiring lab monitoring. This review describes the currently approved NOAC’s.
Authors and Affiliations
PANAYAPPAN L
Syntheses, Characterization and Antimicrobial screening of some Novel Benzimidazoles
Plan: Present work aims to synthesize a series of new benimidazoles (SBS-a-m) with various substitutions at 2-o-amino phenyl position and to evaluate their in-vitro antibacterial and anti-fungal activity. Prologue: Benzi...
A NEW PENTACYCLIC TRITERPENOID WITH ANTIMICROBIAL ACTIVITY FROM THE TUBERS OF Cyperus rotundus Linn.
Plan: The present study is aimed to carry out a phytochemical investigation on Cyperus rotundus Linn tubers and to conduct antimicrobial assays of the isolated phytoconstituents. Methodology: The ethanolic extract of C...
In vitro anti-inflammatory and cytotoxicity studies of two mangrove associated lichens, Dirinaria consimilis and Ramalina leiodea extracts
Plan: To evaluate the anti-inflammatory and cytotoxicity activity of different extracts from two different manglicolous lichens (Dirinaria consimilis and Ramalina leiodea). Preface: Inflammation is the origin of several...
QUALITATIVE ASSESSMENT OF KAYATHIRUMENI - A SIDDHA MEDICATED OIL AS A REMEDY FOR ARTHRITIC PAIN
Plan: Kayathirumeni is an important formulation of Siddha system of medicine used to treat various human disorders. Such as myalgia, Arthritic pain etc. Preface: The present study aimed to set quality parameters in phys...
BIOLOGICAL PROSPECTIVE OF 4-THIAZOLIDINONE: A REVIEW
Plan: Biological prospective of 4-thiazolidinone Prologue: 4-Thiazolidinones are derivatives of thiazolidine with a carbonyl group in the 4thposition. Substitution on the 2nd,3rd and 5thpositions may be varied, but the g...