A REVIEW ON PHARMACOLOGICAL ASPECTS OF MILK THISTLE
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2017, Vol 6, Issue 1
Abstract
Milk thistle is also known as Silybum marianum (Compositae) is widespread throughout the world has been used for the treatment of liver diseases. Its common name comes from the white markings on the leaves and its milky white sap used traditionally by nursing mothers to increase milk. Milk thistle was first cultivated in Europe as vegetable. The de-spined leaves were used in salad and as spinach and the stock; root and flower were also consumed. Silymarin is mixture of flavanoid complex containing silybin, silydianin and siilychrisin that is derived from the milk thistle plant. Silybin have been reported to work as antioxidants scavenging free radicals and inhibiting lipid peroxidation. Milk thistle also act as hepetoprotective agent and it stimulate the protein synthesis. It is orally absorbed but has very poor bioavailability due to poor water solubility. Milk thistle is considered as safe, well tolerated with gastrointestinal tract, mild laxative effect and rare allergic reactions. The review drag the attention of researchers toward the plant for more researches on it.
Authors and Affiliations
Priyanka Thakur
Keywords
Related Articles
- EP ID EP617573
- DOI -
- Views 169
- Downloads 0
A PATIENT WITH HIGH LEVEL OF HEMOGLOBIN A1C (HBA1C) AND CHOLESTEROL WAS PROTECTED FROM ANY COMPLICATIONS BY USING A MIRACLE DIETARY SUPPLEMENT (A2M-SHOPANN SYSTEM)
Complications of uncontrolled diabetes[1] and high cholesterol[2] were prevented completely by daily dietary intake of a combination of several simple food items and changes of life style (A2M-ShopAnn System).[3] Moreove...
EFFECTIVENESS OF SRI LANKAN INDIGENOUS HERBAL SMOKE IN MIGRAINE
Migraine, which is most prevalent neurologic disorder characterized by disabling headache, is highly co-morbid with psychopathological conditions such as depression and anxiety. The aim of this study was to evaluate the...
ANTIRETROVIRAL DRUGS- A GLOBAL SCENARIO AND OVERVIEW
The NRTIS act by competitive inhibition of HIV-1 reverse transcriptase and can also be incorporated into the growing viral DNA chain to cause termination. Each requires intracytoplasmic activation via phosphorylation by...
METHANOLIC EXTRACT OF SPILANTHES CALVA IMPROVES GLIBENCLAMIDE-INDUCED GLUCOSE TOLERANCE
Background. Spilanthes calva is an herbaceous plant found in the wild in Bangladesh. Since the plant’s aerial parts have been previously reported for antihyperglycemic effects, it was of interest to determine whether the...
A REVIEW ARTICLE ON SIGNIFICANCE OF SAMSARJANA KRAMÃ AS PÃSCHÃT KARMÃ
Panchākarma is the highly preferred therapeutic modality to cure any disease with least possibility of recurrence. Panchā karma is always performed in three phases – Pūrva karma (preparatory procedures), Pradhāna karma (...