A Study of Chloride Levels in Cervical Mucosa and Its Correlation with Transvaginal Sonography
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 3
Abstract
Ovarian function can be evaluated by various procedures. Among various constituents of cervical mucus, Sodium Chloride (NaCl) is the major electrolyte responsible for positive fern test at the time of ovulation. The Aim was to evaluate variations in sodium chloride level in cervical mucus and establish a relationship between peak chloride level in cervical mucus by ovulatory& ovulation by premenstrual transvaginal sonography in both infertile and fertile patients. The Study was conducted upon 100 women of reproductive age group with no obvious gynaecological or obstetric disease. There were two groups group I of 50 infertile women and group II of 50 fertile women. History, physical-systemic-gynecological examinations, blood-urine-semen tests, Kahn's test and VDRL test were carried out before enrolment. Each patient was called thrice for TVS and cervical mucus examination. In Results In preovulatory phase, chloride level of all patients were =<0.5%. In periovulatory phase, 40% of both cases showed 0.7%, 6% showed 0.9% in infertile whereas 20% showed 0.9% chloride level in fertile cases. In postovulatory phase, chloride level of all patients were =<0.5%. According to endometrial pattern, 72% infertile and 92% fertile cases showed proliferative endometrium in concordance with follicular size of > 16 mm. 68% infertile and 92% fertile cases showed secretory endometrium which was taken as confirmative of ovulation. For chloride estimation, chloride level estimation detected ovulation in only 72% infertile cases & all fertile cases while cycle was ovulatory in 68%infertile cases & 92% fertile cases according to TVS. In Discussion the Chloride levels in ovulatory cycle were found to be <0.5% in 96% of cases during preovulatory phase, >=0.5% in 72% infertile and all of fertile cases during periovulatory phase, <0.5% in 88% of infertile and all of fertile cases whereas >0.5% in 12% of infertile cases during postovulatory phase. Chloride level estimation of cervical mucus is 96% accurate in infertile and 92% accurate in fertile cases compared to TVS. Keywords: Transvaginal Sonography, Sodium chloride, Ovulation, Cervical mucosa, Infertile, Fertile.
Authors and Affiliations
Dr. Rajani Shrivastava, Dr. Preeti Maheshwari, Dr. S. Sapre
Keywords
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